Neuroprotective activity of natural products isolated from Senecio graciliflorus DC against corticosterone-induced impairment in SH-SY5Y cells.
Sign Up to like & getrecommendations! Published in 2021 at "Naunyn-Schmiedeberg's archives of pharmacology"
DOI: 10.1007/s00210-021-02136-9
Abstract: Senecio graciliflorus DC root extract was studied for secondary metabolite composition following the bioactivity-guided isolation technique. The ethyl acetate extract of Senecio graciliflorus root yielded nine chemical constituents: 3,4-di-tert-butyl toluene, stigmasterol, β-sitosterol, 2β-(angeloyloxy)furanoeremophilane, gallic acid,… read more here.
Keywords: corticosterone induced; graciliflorus; natural products; senecio graciliflorus ... See more keywords
The role of actin depolymerizing factor in advanced glycation endproducts-induced impairment in mouse brain microvascular endothelial cells
Sign Up to like & getrecommendations! Published in 2017 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-017-3019-8
Abstract: Endothelial dysfunction is one of the most important pathological events during the development of several diabetic complications including stroke. The aim of this work was to investigate the role of actin depolymerizing factor (ADF) in… read more here.
Keywords: role actin; actin depolymerizing; mbmecs; induced impairment ... See more keywords
Oxytocin reverses Aβ-induced impairment of hippocampal synaptic plasticity in mice.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.04.046
Abstract: AIM Oxytocin, a peptide hormone synthesized in the hypothalamic paraventricular nucleus, has been reported to participate in the regulation of learning and memory performance. However, no report has demonstrated the effect of oxytocin on the… read more here.
Keywords: induced impairment; synaptic plasticity; plasticity mice; plasticity ... See more keywords
Low frequency electrical stimulation has time dependent improving effect on kindling-induced impairment in long-term potentiation in rats
Sign Up to like & getrecommendations! Published in 2017 at "Brain Research"
DOI: 10.1016/j.brainres.2017.05.007
Abstract: Application of low-frequency stimulation (LFS) can improve learning and memory in kindled animals (Ghafouri et al., 2016). Considering the important role of long-term potentiation (LTP) in learning and memory, in the present study the effectiveness… read more here.
Keywords: kindling induced; stimulation; long term; induced impairment ... See more keywords
ARL15 overexpression attenuates high glucose‐induced impairment of insulin signaling and oxidative stress in human umbilical vein endothelial cells
Sign Up to like & getrecommendations! Published in 2019 at "Life Sciences"
DOI: 10.1016/j.lfs.2019.01.030
Abstract: Aims: Endothelial dysfunction (ED) plays a pivotal role in the development and progression of cardiovascular disease. Recently, genomic studies have found that ARL15, and some of its common genetic variants are associated with type 2… read more here.
Keywords: vein endothelial; human umbilical; high glucose; induced impairment ... See more keywords
Melatonin enhances mitochondrial biogenesis and protects against rotenone‐induced mitochondrial deficiency in early porcine embryos
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pineal Research"
DOI: 10.1111/jpi.12627
Abstract: Melatonin, a major hormone of the pineal gland, exerts many beneficial effects on mitochondria. Several studies have shown that melatonin can protect against toxin‐induced oocyte quality impairment during maturation. However, there is little information regarding… read more here.
Keywords: mitochondrial biogenesis; rotenone; induced impairment; melatonin ... See more keywords
Sleep deprivation‐induced impairment of memory consolidation is not mediated by glucocorticoid stress hormones
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Sleep Research"
DOI: 10.1111/jsr.12972
Abstract: The general consensus is that sleep promotes neuronal recovery and plasticity, whereas sleep deprivation (SD) impairs brain function, including cognitive processes. Indeed, a wealth of data has shown a negative impact of SD on learning… read more here.
Keywords: stress hormones; sleep deprivation; induced impairment; glucocorticoid stress ... See more keywords
Hypothermia Induced Impairment of Platelets: Assessment With Multiplate vs. ROTEM—An In Vitro Study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.852182
Abstract: Introduction: This experimental in vitro study aimed to identify and characterize hypothermia-associated coagulopathy and to compare changes in mild to severe hypothermia with the quantitative measurement of rotational thromboelastometry (ROTEM) and multiple-electrode aggregometry (MULTIPLATE). Methods:… read more here.
Keywords: hypothermia; vitro study; multiplate; induced impairment ... See more keywords
Avicularin Attenuates Lead-Induced Impairment of Hepatic Glucose Metabolism by Inhibiting the ER Stress-Mediated Inflammatory Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14224806
Abstract: Lead (Pb), an environmental hazard, causes several human diseases. Avicularin (Avi), a main dietary flavonoid found in several plants and fruits, exhibits potential protective properties on organs. However, the molecular mechanisms of Avi’s protective effects… read more here.
Keywords: metabolism; stress; induced impairment; hepatic glucose ... See more keywords
Ursolic acid improves the indoxyl sulfate-induced impairment of mitochondrial biogenesis in C2C12 cells
Sign Up to like & getrecommendations! Published in 2022 at "Nutrition Research and Practice"
DOI: 10.4162/nrp.2022.16.2.147
Abstract: BACKGROUND/OBJECTIVES Patients with chronic kidney disease (CKD) have a high concentration of uremic toxins in their blood and often experience muscle atrophy. Indoxyl sulfate (IS) is a uremic toxin produced by tryptophan metabolism. Although an… read more here.
Keywords: c2c12 cells; induced impairment; impairment mitochondrial; mitochondrial biogenesis ... See more keywords