Supplementation‐induced increase in circulating omega‐3 serum levels is not associated with a reduction in depressive symptoms: Results from the MooDFOOD depression prevention trial
Sign Up to like & getrecommendations! Published in 2020 at "Depression and Anxiety"
DOI: 10.1002/da.23092
Abstract: There is ambiguity on how omega‐3 (n‐3) polyunsaturated fatty acids (PUFAs) are associated with depression, and what the temporality of the association might be. The present study aimed to examine whether (intervention‐induced changes in) n‐3… read more here.
Keywords: depressive symptoms; induced increase; increase circulating; circulating omega ... See more keywords
Effects of alcohol-induced increase in CYP2E1 content in human liver microsomes on the activity and cooperativity of CYP3A4.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2020.108677
Abstract: We investigate the effect of the alcohol-induced increase in the content of CYP2E1 in human liver microsomes (HLM) on the function of CYP3A4. Membrane incorporation of the purified CYP2E1 into HLM considerably increases the rate… read more here.
Keywords: induced increase; cyp2e1; hlm; alcohol induced ... See more keywords
Discovery of Selective Pituitary Adenylate Cyclase 1 Receptor (PAC1R) Antagonist Peptides Potent in a Maxadilan/PACAP38-Induced Increase in Blood Flow Pharmacodynamic Model.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.0c01396
Abstract: Inhibition of the pituitary adenylate cyclase 1 receptor (PAC1R) is a novel mechanism that could be used for abortive treatment of acute migraine. Our research began with comparative analysis of known PAC1R ligand scaffolds, PACAP38… read more here.
Keywords: induced increase; maxadilan; cyclase receptor; pituitary adenylate ... See more keywords
Role of Phospholipase C in Catecholamine-induced Increase in Myocardial Protein Synthesis.
Sign Up to like & getrecommendations! Published in 2022 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2022-0189
Abstract: The activation of the α1-adrenoceptor-(α1-AR) by norepinephrine results in the G-protein (Gqα) mediated increase in the phosphoinositide-specific phospholipase C (PLC) activity. The byproducts of PLC hydrolytic activity, namely, 1,2-diacylglycerol and inositol-1,4,5-trisphosphate, are important downstream signal… read more here.
Keywords: phospholipase; increase; catecholamine induced; induced increase ... See more keywords
Metabolic Reprogramming in Cancer is Induced to Increase Proton Production.
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DOI: 10.1158/0008-5472.can-19-3392
Abstract: Considerable metabolic reprogramming has been observed in a conserved manner across multiple cancer types, but their true causes remain elusive. We present an analysis of around 50 such reprogrammed metabolisms (RMs) including the Warburg effect,… read more here.
Keywords: reprogramming cancer; metabolic reprogramming; induced increase; cancer induced ... See more keywords
Melatonin-Activated Receptor Signaling Pathways Mediate Protective Effects on Surfactant-Induced Increase in Jejunal Mucosal Permeability in Rats
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DOI: 10.3390/ijms221910762
Abstract: A well-functional intestinal mucosal barrier can be compromised as a result of various diseases, chemotherapy, radiation, and chemical exposures including surfactants. Currently, there are no approved drugs targeting a dysfunctional intestinal barrier, which emphasizes a… read more here.
Keywords: induced increase; mucosal; surfactant induced; mucosal permeability ... See more keywords
Spawning-Induced pH Increase Activates Sperm Attraction and Fertilization Abilities in Eggs of the Ascidian, Phallusia philippinensis and Ciona intestinalis
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032666
Abstract: In Phlebobranchiata ascidians, oocytes and spermatozoa are stored in the oviduct and spermiduct, respectively, until spawning occurs. Gametes in the gonoducts are mature and fertilizable; however, it was found that the gametes of the ascidians… read more here.
Keywords: fertilization; increase; ciona intestinalis; induced increase ... See more keywords