Letter to the Editor: The Potential Mechanism by the Protection Effects of Exercise Training on Ischemia/Reperfusion–Induced Injury and Metastasis
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.31854
Abstract: We read with great interest the recently published article by Yazdani et al. (1) demonstrating the protection effects of exercise training on liver I/R-induced injury and metastasis. It's a meaningful study proposing exercise training as… read more here.
Keywords: injury metastasis; metastasis; induced injury; effects exercise ... See more keywords
Schizandrin protects H9c2 cells against lipopolysaccharide‐induced injury by downregulating Smad3
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22301
Abstract: Schizandrin is a major bioactive constituent of Schisandra chinensis (Turcz.) Baill with antioxidant and anti‐inflammatory properties. The objective of this study was to explore the potential effects of schizandrin on a cell model of myocarditis.… read more here.
Keywords: h9c2 cells; downregulating smad3; induced injury; schizandrin ... See more keywords
Ox-LDL aggravates contrast-induced injury of renal tubular epithelial cells.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.23379
Abstract: Hypercholesterolemia can aggravate contrast-induced acute kidney injury, and the exacerbation of renal tubular epithelial cell (RTEC) injury is a major cause. However, the exact mechanisms remain obscure. Mitophagy, a type of autophagy, selectively eliminates damaged… read more here.
Keywords: induced injury; contrast induced; renal tubular; mitophagy ... See more keywords
Deletion of long noncoding RNA EFNA3 aggravates hypoxia‐induced injury in PC‐12 cells by upregulation of miR‐101a
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27444
Abstract: Long noncoding RNAs (lncRNAs) have been reported to be involved in several neurological pathogenesis conditions including cerebral ischemia. In the current study, the functions of lncRNA EFNA3 on hypoxia‐injured rat adrenal pheochromocytoma (PC‐12) cells and… read more here.
Keywords: lncrna efna3; mir 101a; induced injury; hypoxia induced ... See more keywords
Bone marrow mesenchymal stem cells‐derived conditioned medium protects cardiomyocytes from hypoxia/reoxygenation‐induced injury through Notch2/mTOR/autophagy signaling
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28530
Abstract: Bone marrow mesenchymal stem cells (BMSC) can ameliorate ischemic injury of various tissues. However, the molecular mechanisms involved remain to be clarified. In this study, we intend to investigate the effects of BMSC‐derived conditioned medium… read more here.
Keywords: induced injury; marrow mesenchymal; mtor; mesenchymal stem ... See more keywords
Fenamates Inhibit Human Sodium Channel Nav1.2 and Protect Glutamate-Induced Injury in SH-SY5Y Cells
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DOI: 10.1007/s10571-020-00826-1
Abstract: Abstract Voltage-gated sodium channels are crucial mediators of neuronal damage in ischemic and excitotoxicity disease models. Fenamates have been reported to have anti-inflammatory properties following a decrease in prostaglandin synthesis. Several researches showed that fenamates… read more here.
Keywords: induced injury; glutamate induced; injury sy5y; sy5y cells ... See more keywords
New triterpenoids from Staphylea bumalda flower buds and their neuroprotective activity against H2O2-induced injury in vitro
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Pharmacal Research"
DOI: 10.1007/s12272-018-1086-3
Abstract: Four new acylated triterpene glycosides with aliphatic chains (4–7) as well as five known triterpenoids were isolated from the flower buds of Staphylea bumalda with bioassay guidance. Their structures were determined on the basis of… read more here.
Keywords: staphylea bumalda; induced injury; flower buds; new triterpenoids ... See more keywords
LncRNA SNHG1 alleviates OGD induced injury in BMEC via miR-338/HIF-1α axis
Sign Up to like & getrecommendations! Published in 2019 at "Brain Research"
DOI: 10.1016/j.brainres.2018.11.003
Abstract: BACKGROUND Brain microvascular endothelial cell (BMEC) is an important therapeutic target for the inhibition of brain vascular dysfunction in ischemic stroke. Expression of long non-coding RNA SNHG1 is reportedly upregulated in BMEC after OGD. The… read more here.
Keywords: snhg1; ogd induced; bmec; induced injury ... See more keywords
NGF protects endothelial cells from indomethacin-induced injury through activation of mitochondria and upregulation of IGF-1.
Sign Up to like & getrecommendations! Published in 2017 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2017.08.006
Abstract: BACKGROUND/AIMS Endothelial cells (ECs) lining blood vessels are critical for delivery of oxygen and nutrients to all tissues and organs and play a crucial role in the regeneration of blood vessel following tissue injury. ECs… read more here.
Keywords: indo; gecs; induced injury; mitochondria ... See more keywords
Marein protects human nucleus pulposus cells against high glucose-induced injury and extracellular matrix degradation at least partly by inhibition of ROS/NF-κB pathway.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2019.106126
Abstract: Intervertebral disc degeneration (IDD), a major cause of discogenic low back pain, is a musculoskeletal disorder involving the apoptosis of nucleus pulposus cells (NPCs) and extracellular matrix (ECM) degradation. Marein is a major active flavonoid… read more here.
Keywords: hnpcs; degradation; induced injury; ecm degradation ... See more keywords
Senkyunolide H protects PC12 cells from OGD/R-induced injury via cAMP-PI3K/AKT signaling pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2021.114659
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Senkyunolide H (SNH) is a bioactive phthalide isolated from Ligusticum chuanxiong Hort rhizome and was reported to have multiple pharmacological effects. AIM OF THE STUDY The study was performed to verify the potency… read more here.
Keywords: camp; pc12 cells; ogd induced; cells ogd ... See more keywords