Changes in the TCR repertoire of T‐cell subsets during culture of cytokine‐induced killer cells
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14501
Abstract: Cytokine‐induced killer (CIK) cells are a group of highly heterogeneous T cells expressing diverse T‐cell antigen receptors (TCRs), but possessing wide major histocompatibility complex (MHC)‐unrestricted antitumour activity, which have been used in the treatment of… read more here.
Keywords: cell subsets; induced killer; cell; cytokine induced ... See more keywords
Cancer Immunotherapy with Cytokine-Induced Killer Cells
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DOI: 10.1007/s11523-017-0489-2
Abstract: AbstractCytokine-induced killer (CIK) cells form under certain stimulation conditions in cultures of peripheral blood mononuclear cells (PBMCs). They are a heterogeneous immune cell population and contain a high percentage of cells with a mixed T-NK… read more here.
Keywords: induced killer; cancer immunotherapy; killer; cik cells ... See more keywords
P09.01 Adoptive cell therapy of hematological malignancies using cytokine-induced killer cells retargeted with monoclonal antibodies
Sign Up to like & getrecommendations! Published in 2020 at "Journal for ImmunoTherapy of Cancer"
DOI: 10.1136/jitc-2020-itoc7.101
Abstract: Background Cytokine-Induced Killer (CIK) cells are a population of effector cells that represents a promising tool for adoptive cell therapy. They are easily expandable ex-vivo , safe, and exert cytotoxicity against a broad range of… read more here.
Keywords: none; cytokine induced; induced killer; cell ... See more keywords
Improving cytokine-induced killer cell expansion using a gas-permeable culture method for clinical-scale production.
Sign Up to like & getrecommendations! Published in 2023 at "Asian Pacific journal of allergy and immunology"
DOI: 10.12932/ap-190822-1437
Abstract: BACKGROUND Cytokine-induced killer (CIK) cells are a heterogeneous group of immune cells that exert potent MHC-unrestricted cytotoxicity toward various cancer cells in both solid and hematological malignancies. OBJECTIVE The purposes of this study were to… read more here.
Keywords: culture method; induced killer; cytokine induced;
Cytokine-induced killer cell delivery enhances the antitumor activity of oncolytic reovirus
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DOI: 10.1371/journal.pone.0184816
Abstract: Oncolytic viruses (OV) have recently emerged as a promising therapeutic modality in cancer treatment. OV selectively infect and kill tumor cells, while sparing untransformed cells. The direct cytotoxic effects combined with the capacity to trigger… read more here.
Keywords: reovirus; cytokine induced; induced killer; activity ... See more keywords
Immunophenotype and antitumor activity of cytokine-induced killer cells from patients with hepatocellular carcinoma
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DOI: 10.1371/journal.pone.0280023
Abstract: Background Cytokine-induced killer (CIK) cells are heterogeneous lymphocytes from human peripheral blood mononucleated cells (PBMCs) co-cultured with several cytokines. The main purpose of this study is to evaluate the functional characteristics and anticancer ability of… read more here.
Keywords: ability; cik; cytokine induced; cik cells ... See more keywords
Current update of adoptive immunotherapy using cytokine-induced killer cells to eliminate malignant gliomas.
Sign Up to like & getrecommendations! Published in 2017 at "Immunotherapy"
DOI: 10.2217/imt-2017-0003
Abstract: The therapeutic outcome for those with malignant glioma is poor, even though diverse therapeutic modalities have been developed. Immunotherapy has emerged as a therapeutic approach for malignant gliomas, making it possible to selectively treat tumors… read more here.
Keywords: immunotherapy; malignant gliomas; adoptive immunotherapy; cytokine induced ... See more keywords
Cytokine-Induced Killer Cells As Pharmacological Tools for Cancer Immunotherapy
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DOI: 10.3389/fimmu.2017.00774
Abstract: Cytokine-induced killer (CIK) cells are a heterogeneous population of effector CD3+CD56+ natural killer T cells, which can be easily expanded in vitro from peripheral blood mononuclear cells. CIK cells work as pharmacological tools for cancer… read more here.
Keywords: killer; cik cells; cytokine induced; induced killer ... See more keywords
Clinical Studies Applying Cytokine-Induced Killer Cells for the Treatment of Renal Cell Carcinoma
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DOI: 10.3390/cancers12092471
Abstract: Simple Summary Cytokine-induced killer (CIK) cells are a heterogeneous population of polyclonal T effector cells expanded ex vivo. Here, we updated our last review published in 2012 and provided a synopsis of current 15 clinical… read more here.
Keywords: cik cell; cytokine induced; cik; induced killer ... See more keywords