Glucocorticoid-Induced Leucine Zipper as a Druggable Target in Inflammatory Bowel Diseases.
Sign Up to like & getrecommendations! Published in 2020 at "Inflammatory bowel diseases"
DOI: 10.1093/ibd/izz331
Abstract: Inflammatory bowel diseases (IBDs) are chronic inflammatory disorders with a complex pathogenesis, affecting people of all ages. They are characterized by alternating phases of clinical relapse and remission, depending on the fine balance between immune… read more here.
Keywords: leucine zipper; inflammatory bowel; glucocorticoid induced; bowel diseases ... See more keywords
Glucocorticoid-Induced Leucine Zipper: A Promising Marker for Monitoring and Treating Sepsis
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.606649
Abstract: Sepsis is a clinical syndrome that resulting from a dysregulated inflammatory response to infection that leads to organ dysfunction. The dysregulated inflammatory response transitions from a hyper-inflammatory phase to a hypo-inflammatory or immunosuppressive phase. Currently,… read more here.
Keywords: sepsis; leucine zipper; glucocorticoid induced; gilz ... See more keywords
Glucocorticoid-Induced Leucine Zipper: A Novel Anti-inflammatory Molecule
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2019.00308
Abstract: Glucocorticoids (GCs) are the most commonly used drugs for treatment of autoimmune and inflammatory diseases. Their efficacy is due to their ability to bind cytoplasmic receptors (glucocorticoid receptors, GR) and other cytoplasmic proteins, thus regulating… read more here.
Keywords: anti inflammatory; leucine zipper; glucocorticoid induced; gilz ... See more keywords