Regulation of microRNA-29c in the nucleus accumbens modulates methamphetamine -induced locomotor sensitization in mice
Sign Up to like & getrecommendations! Published in 2019 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2019.01.007
Abstract: ABSTRACT Changes in microRNA (miRNA)‐mediated gene expression in the nucleus accumbens (NAc) may play important roles in regulating drug addiction. MiR‐29c is a highly expressed miRNA in the human and rodent nervous systems where it… read more here.
Keywords: induced locomotor; meth induced; expression; locomotor sensitization ... See more keywords
Cardiolipin and OPA1 Team up for Methamphetamine-Induced Locomotor Activity by Promoting Neuronal Mitochondrial Fusion in the Nucleus Accumbens of Mice.
Sign Up to like & getrecommendations! Published in 2023 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.2c00709
Abstract: Mitochondria are highly dynamic organelles with coordinated cycles of fission and fusion occurring continuously to satisfy the energy demands in the complex architecture of neurons. How mitochondria contribute to addicted drug-induced adaptable mitochondrial networks and… read more here.
Keywords: induced locomotor; fusion; opa1; neuronal mitochondrial ... See more keywords
Methamphetamine-induced locomotor sensitization in mice is not associated with deficits in a range of cognitive, affective and social behaviours: interaction with brain-derived neurotrophic factor Val66Met genotype
Sign Up to like & getrecommendations! Published in 2022 at "Behavioural Pharmacology"
DOI: 10.1097/fbp.0000000000000708
Abstract: Chronic methamphetamine (Meth) abuse may induce psychosis similar to that observed in schizophrenia. Brain-derived neurotrophic factor (BDNF) has been implicated in the development of psychosis. We have previously shown long-term protein expression changes in mice… read more here.
Keywords: induced locomotor; brain derived; social behaviours; locomotor ... See more keywords
Reassessment of amphetamine- and phencyclidine-induced locomotor hyperactivity as a model of psychosis-like behavior in rats.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of integrative neuroscience"
DOI: 10.31083/j.jin2101017
Abstract: Locomotor hyperactivity induced by psychotomimetic drugs, such as amphetamine and phencyclidine, is widely used as an animal model of psychosis-like behaviour and is commonly attributed to an interaction with dopamine release and N-methyl-D-aspartate (NMDA) receptors,… read more here.
Keywords: induced locomotor; locomotor hyperactivity; hyperactivity; amphetamine phencyclidine ... See more keywords
Minocycline Attenuates Lipopolysaccharide-Induced Locomotor Deficit and Anxiety-like Behavior and Related Expression of the BDNF/CREB Protein in the Rat Medial Prefrontal Cortex (mPFC)
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232113474
Abstract: Neuroinflammation following lipopolysaccharide (LPS) administration induces locomotor deficits and anxiety-like behaviour. In this study, minocycline was compared to memantine, an NMDA receptor antagonist, for its effects on LPS-induced locomotor deficits and anxiety-like behaviour in rats.… read more here.
Keywords: induced locomotor; like behaviour; anxiety like; creb protein ... See more keywords
Glycogen Synthase Kinase 3β Is a Key Regulator in the Inhibitory Effects of Accumbal Cocaine- and Amphetamine-Regulated Transcript Peptide 55–102 on Amphetamine-Induced Locomotor Activity
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232415633
Abstract: Microinjection of cocaine- and amphetamine-regulated transcript (CART) peptide 55–102 into the nucleus accumbens (NAcc) core significantly attenuates psychostimulant-induced locomotor activity. However, the molecular mechanism remains poorly understood. We examined the phosphorylation levels of Akt, glycogen… read more here.
Keywords: locomotor activity; induced locomotor; amphetamine; peptide 102 ... See more keywords