In vivo Structure‐Activity Relationship of Dihydromethysticin in Reducing Nicotine‐Derived Nitrosamine Ketone (NNK)‐Induced Lung DNA Damage against Lung Carcinogenesis in A/J Mice
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DOI: 10.1002/cmdc.202100727
Abstract: Lung cancer is the leading cause of cancer‐related deaths and chemoprevention should be developed. We recently identified dihydromethysticin (DHM) as a promising candidate to prevent NNK‐induced lung tumorigenesis. To probe its mechanisms and facilitate its… read more here.
Keywords: lung; dna damage; induced lung; nnk induced ... See more keywords
Protective effect of vanillic acid against benzo(a)pyrene induced lung cancer in Swiss albino mice
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22382
Abstract: Vanillic acid (VA) is found in high concentrations in various plants and used as traditional medicine for various diseases. The aim of the existing study is to illustrate the protective effects of VA against benzo(a)pyrene… read more here.
Keywords: vanillic acid; pyrene induced; benzo pyrene; induced lung ... See more keywords
Protective effects of fargesin on cadmium‐induced lung injury through regulating aryl hydrocarbon receptor
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DOI: 10.1002/jbt.23197
Abstract: Fragesin, a traditional Chinese medicine, has been shown to exert anti‐inflammatory effect. The aim of this study was to figure out the possible effectiveness of the fargesin, and to invest the mechanisms by which it… read more here.
Keywords: cadmium induced; lung injury; cadmium; induced lung ... See more keywords
Expression profiling analysis of long noncoding RNAs in a mouse model of ventilator‐induced lung injury indicating potential roles in inflammation
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DOI: 10.1002/jcb.28446
Abstract: The key regulators of inflammation underlying ventilator‐induced lung injury (VILI) remain poorly defined. Long noncoding RNAs (lncRNAs) have been implicated in the inflammatory response of many diseases; however, their roles in VILI remain unclear. We,… read more here.
Keywords: ventilator induced; analysis; inflammation; induced lung ... See more keywords
Curcumin Alleviated Lipopolysaccharide-Induced Lung Injury Via Regulating Nrf2-ARE and NF-κB Signaling Pathways in Ducks.
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DOI: 10.1002/jsfa.12027
Abstract: BACKGROUND Under the intensive modern poultry farming system, the lung of duck is one of the main targeted organs for various bacterial and viral infections. Curcumin is a kind of natural polyphenol compound which exist… read more here.
Keywords: lung injury; curcumin; nrf2 signaling; induced lung ... See more keywords
Time‐dependent effect of inhaled cigarette smoke exposure in the bleomycin‐induced lung injury rat model
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DOI: 10.1002/tox.23479
Abstract: Cigarette smoke (CS) substances are known to induce diverse ailments such as cancer, decreased immunity, and lung diseases. Although some studies have been actively conducted to evaluate cigarette toxicity, the current animal exposure methods, that… read more here.
Keywords: exposure; rat model; model; induced lung ... See more keywords
Gossypin exert lipopolysaccharide induced lung inflammation via alteration of Nrf2/HO-1 and NF-κB signaling pathway.
Sign Up to like & getrecommendations! Published in 2023 at "Environmental toxicology"
DOI: 10.1002/tox.23806
Abstract: Acute Lung Injury (ALI) is a critical medical condition that induces the injury into the lung tissue, resulting in decreased the oxygen levels in the circulation and finally causes the respiratory failure. In this study,… read more here.
Keywords: lung tissue; gossypin; lung; lung inflammation ... See more keywords
Linking Physiological Biomarkers of Ventilator-Induced Lung Injury to a Rich-Get-Richer Mechanism of Injury Progression
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DOI: 10.1007/s10439-018-02165-1
Abstract: Mechanical ventilation is a crucial tool in the management of acute respiratory distress syndrome, yet it may itself also further damage the lung in a phenomenon known as ventilator-induced lung injury (VILI). We have previously… read more here.
Keywords: ventilator induced; induced lung; get richer; lung injury ... See more keywords
The Fatty Acid Amide Hydrolase Inhibitor URB937 Ameliorates Radiation-Induced Lung Injury in a Mouse Model
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DOI: 10.1007/s10753-017-0568-7
Abstract: Radiation-induced lung injury (RILI) is a potentially life-threatening complication of radiotherapy. In the current study, we examined the potential protective effects of URB937, an inhibitor of fatty acid amide hydrolase using a mouse model of… read more here.
Keywords: radiation induced; lung injury; fatty acid; induced lung ... See more keywords
Protective Effects of Acupuncture in Cardiopulmonary Bypass-Induced Lung Injury in Rats
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DOI: 10.1007/s10753-017-0570-0
Abstract: Acute lung injury caused by cardiopulmonary bypass (CPB) increases the mortality after cardiac surgery. Our previous clinical study suggested that electroacupuncture (EAc) has a protective effect during CPB, but the mechanism was unclear. So, we… read more here.
Keywords: caspase; cpb; induced lung; lung injury ... See more keywords
Protective Effects of Neural Crest-Derived Stem Cell-Conditioned Media against Ischemia-Reperfusion-Induced Lung Injury in Rats
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DOI: 10.1007/s10753-017-0594-5
Abstract: Current treatments for ischemia-reperfusion (IR)-induced acute lung injury are limited. Mesenchymal stem cell-conditioned medium (CM) has been reported to attenuate lung injury. Neural crest stem cells (NCSCs), a type of multipotent stem cells, are more… read more here.
Keywords: reperfusion; induced lung; stem; lung injury ... See more keywords