Iguratimod ameliorates nephritis by modulating the Th17/Treg paradigm in pristane-induced lupus.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.107563
Abstract: OBJECTIVE Iguratimod, an anti-rheumatic drug, has been widely used in the treatment of rheumatoid arthritis, but is still at an investigative stage for treatment of systemic lupus erythematosus (SLE). We examined the therapeutic effects of… read more here.
Keywords: th17 treg; pristane induced; induced lupus; iguratimod ... See more keywords
A case of lupus‐like syndrome in a patient receiving adalimumab and a brief review of the literature on drug‐induced lupus erythematosus
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Pharmacy and Therapeutics"
DOI: 10.1111/jcpt.12506
Abstract: Drug‐induced lupus erythematosus occurs with some drugs and resolves with their withdrawal. Anti‐TNF therapies have been found to be associated with a lupus‐like syndrome, which is clinically distinct from classical drug‐induced as well as idiopathic… read more here.
Keywords: lupus like; lupus erythematosus; induced lupus; drug induced ... See more keywords
Drug-induced lupus erythematosus following immunotherapy with anti-programmed death-(ligand) 1
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-213677
Abstract: We read with interest the study of Kostine et al describing rheumatic immune-related adverse events (irAE), which occur in 6.6% of patients treated for cancer by anti-programmed death-(ligand) 1 (PDL1).1 These new adverse effects pose significant challenges… read more here.
Keywords: anti; drug induced; induced lupus; programmed death ... See more keywords
AB0155 1,25 dihydroxyvitamin d supplementation reduces hind paw edema in pristane-induced lupus model
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.6619
Abstract: Background Systemic lupus erythematosus (SLE) is a multifactorial, autoimmune inflammatory disease with pleomorphic clinical manifestations involving different organs and tissues. Vitamin D (VITD) deficiency is highly prevalent and evidence is mounting that it contributes to… read more here.
Keywords: supplementation; pristane induced; vitd; induced lupus ... See more keywords
MicroRNA 155-deficiency leads to decreased autoantibody levels and reduced severity of nephritis and pneumonitis in pristane-induced lupus
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0181015
Abstract: Objective We herein examine the role of endogenous miR155 in the development of systemic manifestations in pristane induced lupus. Materials and methods Systemic lupus in miR155-deficient and wild type mice was induced upon injection of… read more here.
Keywords: pristane induced; pristane; induced lupus; mice ... See more keywords
Peptidylarginine Deiminase 4 Promotes the Renal Infiltration of Neutrophils and Exacerbates the TLR7 Agonist-Induced Lupus Mice
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.01095
Abstract: Peptidylarginine deiminase 4 (PAD4), encoded by PADI4, plays critical roles in the immune system; however, its contribution to the pathogenesis of lupus nephritis remains controversial. The pathological roles of PAD4 were investigated in lupus model… read more here.
Keywords: infiltration; padi4 neutrophils; induced lupus; p38 ... See more keywords