Proteomic Profiling of LPS‐Induced Macrophage‐Derived Exosomes Indicates Their Involvement in Acute Liver Injury
Sign Up to like & getrecommendations! Published in 2019 at "PROTEOMICS"
DOI: 10.1002/pmic.201800274
Abstract: Exosomes are typically involved in cellular communication and signaling. Macrophages play a key role in lipopolysaccharide (LPS)‐induced sepsis. However, the molecular comparison of exosomes derived from LPS‐induced macrophage has not been well analyzed. The macrophage‐exosomes… read more here.
Keywords: macrophage exosomes; lps induced; macrophage derived; induced macrophage ... See more keywords
Aloperine suppresses LPS-induced macrophage activation through inhibiting the TLR4/NF-κB pathway
Sign Up to like & getrecommendations! Published in 2020 at "Inflammation Research"
DOI: 10.1007/s00011-019-01313-0
Abstract: Objective The currently available anti-inflammatory drugs often cause diverse side effects with long-term use. Exploring anti-inflammatory drugs with better efficacy and lower toxicity presents an ongoing challenge. Aloperine is an alkaloid extracted from the leaves… read more here.
Keywords: aloperine suppresses; lps induced; macrophage activation; induced macrophage ... See more keywords
Blockade of CD38 diminishes lipopolysaccharide-induced macrophage classical activation and acute kidney injury involving NF-κB signaling suppression.
Sign Up to like & getrecommendations! Published in 2018 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2017.10.014
Abstract: The CD38, possessing ADP-ribosyl cyclase (ADPR-cyclase) and cyclic ADP-ribose hydrolase (cADPR-hydrolase), is able to regulate a variety of cellular activities. However, the role and mechanisms for CD38 in macrophage activation and sepsis-induced acute kidney injury… read more here.
Keywords: kidney injury; cd38; acute kidney; induced macrophage ... See more keywords
Induced macrophage activation in live excised atherosclerotic plaque.
Sign Up to like & getrecommendations! Published in 2018 at "Immunobiology"
DOI: 10.1016/j.imbio.2018.03.002
Abstract: Atherosclerotic plaques are complex tissues containing many different cell types. Macrophages contribute to inflammation, formation of the necrotic core, and plaque rupture. We examined whether macrophages in plaque can be activated and compared this to… read more here.
Keywords: plaque; induced macrophage; total neopterin; macrophage activation ... See more keywords
Cathelicidin‐WA polarizes E. coli K88‐induced M1 macrophage to M2‐like macrophage in RAW264.7 cells
Sign Up to like & getrecommendations! Published in 2018 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2017.10.013
Abstract: ABSTRACT Immune cells ‐ macrophages induced by E. coli K88 will lead to a pro‐inflammatory response, which is important in host defense. Cathelicidin‐WA (CWA) is an efficient antimicrobial peptide (AMP) and can exert immunomodulatory properties.… read more here.
Keywords: k88 induced; coli k88; induced macrophage; macrophage ... See more keywords
Immunometabolism: Stress-induced macrophage polarization
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Immunology"
DOI: 10.1038/nri.2017.41
Abstract: Activation of the IRE1α-mediated stress response pathway in adipose tissue macrophages suppresses M2 polarization. read more here.
Keywords: immunometabolism stress; macrophage polarization; polarization; stress induced ... See more keywords
Chemokine-Induced Macrophage Polarization in Inflammatory Conditions
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.01930
Abstract: Macrophages represent a heterogeneous cell population and are known to display a remarkable plasticity. In response to distinct micro-environmental stimuli, e.g., tumor stroma vs. infected tissue, they polarize into different cell subtypes. Originally, two subpopulations… read more here.
Keywords: macrophage polarization; chemokine induced; polarization; polarization inflammatory ... See more keywords
Hydrogen sulfide attenuates TMAO‑induced macrophage inflammation through increased SIRT1 sulfhydration
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2023.13016
Abstract: Chronic inflammation is a key factor that accelerates the progression of inflammatory vascular disease. Hydrogen sulfide (H2S) has potent anti-inflammatory effects; however, its underlying mechanism of action has not been fully elucidated. The present study… read more here.
Keywords: inflammation; induced macrophage; tmao induced; sirt1 sulfhydration ... See more keywords