Bone marrow‐derived mesenchymal stem cells alleviate paclitaxel‐induced mechanical allodynia in rats
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23207
Abstract: Anticancer drug paclitaxel (PTX) frequently causes painful peripheral neuropathy; however, no medication has been shown to be effective in the treatment of this debilitating side effect. We aimed to investigate the efficacy of two different… read more here.
Keywords: ptx; induced mechanical; bone marrow; allodynia ... See more keywords
TAFA4 relieves injury-induced mechanical hypersensitivity through LDL receptors and modulation of spinal A-type K+ current.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109884
Abstract: Pain, whether acute or persistent, is a serious medical problem worldwide. However, its management remains unsatisfactory, and new analgesic molecules are required. We show here that TAFA4 reverses inflammatory, postoperative, and spared nerve injury (SNI)-induced… read more here.
Keywords: induced mechanical; mechanical hypersensitivity; tafa4; type current ... See more keywords
A new concept of the mechanism of tribocatalytic reactions induced by mechanical forces
Sign Up to like & getrecommendations! Published in 2017 at "Tribology International"
DOI: 10.1016/j.triboint.2016.08.022
Abstract: Abstract The aim of this paper is to present a new approach to the mechanism of tribocatalytic reactions induced by mechanical forces. The new concept is based on the authors’ previous research, which reveals that… read more here.
Keywords: reactions induced; induced mechanical; tribocatalytic reactions; mechanical forces ... See more keywords
Touch-induced mechanical strain in somatosensory neurons is independent of extracellular matrix mutations in Caenorhabditis elegans
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e20-01-0049
Abstract: Cutaneous mechanosensory neurons are activated by mechanical loads applied to the skin, and these stimuli are proposed to generate mechanical strain within sensory neurons. Using a microfluidic device to deliver controlled stimuli to intact animals… read more here.
Keywords: touch induced; mechanical strain; induced mechanical; caenorhabditis elegans ... See more keywords
Chemokine CCL2 and its receptor CCR2 in the dorsal root ganglion contribute to oxaliplatin-induced mechanical hypersensitivity
Sign Up to like & getrecommendations! Published in 2018 at "PAIN"
DOI: 10.1097/j.pain.0000000000001212
Abstract: Abstract Activation of innate immune mechanisms within the dorsal root ganglion and spinal dorsal horn has been shown to play a key role in the development of neuropathic pain including paclitaxel-related chemotherapy-induced peripheral neuropathy (CIPN).… read more here.
Keywords: oxaliplatin induced; induced mechanical; root ganglion; ccl2 ... See more keywords
Cell-specific role of HDAC6 in chemotherapy-induced mechanical allodynia and loss of intraepidermal nerve fibers.
Sign Up to like & getrecommendations! Published in 2019 at "Pain"
DOI: 10.1097/j.pain.0000000000001667
Abstract: Chemotherapy-induced peripheral neuropathy (CIPN) is a serious adverse side effect of cancer treatment with no FDA-approved medication for its prevention or management. Using RNA sequencing analysis of dorsal root ganglia (DRG) we identify critical contributions… read more here.
Keywords: induced mechanical; cisplatin induced; allodynia; mechanical allodynia ... See more keywords
Sympathectomy Ameliorates CFA-Induced Mechanical Allodynia via Modulating Phenotype of Macrophages in Sensory Ganglion in Mice
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s388322
Abstract: Background The sympathetic nervous system (SNS) is suggested to be involved in some forms of pain, but the mechanisms of which are incompletely known. Moreover, there is a lack of information on the regulatory role… read more here.
Keywords: macrophages sensory; ganglion; induced mechanical; cfa induced ... See more keywords