miR-let-7a suppresses α-Synuclein-induced microglia inflammation through targeting STAT3 in Parkinson's disease.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.08.140
Abstract: Microglia-mediated neuroinflammation is critical for the pathogenesis of neurodegenerative diseases, including Parkinson's disease (PD). microRNA-let-7a (miR-let-7a) targets the signal transducer and activator of transcription-3 (STAT3) and regulates microglia function. However, less is known about whether… read more here.
Keywords: let suppresses; mir let; inflammation targeting; targeting stat3 ... See more keywords
Fibromyalgia and microglial TNF-α: Translational research using human blood induced microglia-like cells
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-11506-4
Abstract: Fibromyalgia is a refractory disease characterized by chronic intractable pain and psychological suffering, the cause of which has not yet been elucidated due to its complex pathology. Activation of immune cells in the brain called… read more here.
Keywords: using human; research using; img cells; pathology ... See more keywords