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Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.25938
Abstract: It is has been demonstrated that mitochondrial dysfunction, oxidative stress, and chronic inflammatory process are associated with progress of morbid obesity in human patients. For this reason, the searching for safe and effective antiobesity drugs…
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Keywords:
induced monosodium;
mitochondrial function;
monosodium glutamate;
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Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2072055
Abstract: ABSTRACT The study is aimed to determine the effects of cynarin (Cyn) on mice with gouty arthritis (GA) induced by monosodium urate (MSU). We measured swelling in the hind paws of mice in vivo using…
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Keywords:
hind paws;
monosodium urate;
induced monosodium;
gouty arthritis ... See more keywords
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Published in 2021 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s318540
Abstract: Objective To explore whether methotrexate (MTX) prevents joint destruction and improves pain-related behaviors in the acute phase of knee osteoarthritis (OA) induced by monosodium iodoacetate (MIA) in a rat model. Methods Twenty of 25 male…
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Keywords:
osteoarthritis induced;
pain related;
induced monosodium;
knee osteoarthritis ... See more keywords
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Published in 2025 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics17101254
Abstract: Background/Objectives: Osteoarthritis (OA) is a progressive joint disease characterized by inflammation, cartilage degradation, and subchondral bone changes, for which effective disease-modifying therapies are lacking. Messenger RNA (mRNA)-based therapeutics offer a versatile approach to modulate joint…
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Keywords:
mrna based;
induced monosodium;
pathology;
monosodium iodoacetate ... See more keywords