CHARACTERIZATION OF THE ANTIAPOPTOTIC EFFECT OF COPPER SULFATE ON STRIATAL AND MIDBRAIN DAMAGE INDUCED BY MPP+IN RATS.
Sign Up to like & getrecommendations! Published in 2020 at "Neurotoxicology"
DOI: 10.1016/j.neuro.2020.10.011
Abstract: 1-Methyl-4-phenylpyridinium ion (MPP+)-induced neurotoxicity produces cellular damage resembling that encountered in Parkinson's disease. The mechanisms of cellular death after MPP+ include the participation of oxidative stress in the loss of dopaminergic neurons. Among the mechanisms… read more here.
Keywords: induced mpp; copper; copper sulfate; damage ... See more keywords
NaSH increases SIRT1 activity and autophagy flux through sulfhydration to protect SH-SY5Y cells induced by MPP~+
Sign Up to like & getrecommendations! Published in 2020 at "Cell Cycle"
DOI: 10.1080/15384101.2020.1804179
Abstract: ABSTRACT Parkinson’s disease (PD) is one of the most prevailing aging diseases around the world. The present study was to investigate the potential effect of hydrogen sulfide (H2S) and silent mating type information regulation 2… read more here.
Keywords: cells induced; induced mpp; sy5y cells; h2s ... See more keywords
Bacopa Protects against Neurotoxicity Induced by MPP+ and Methamphetamine
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DOI: 10.3390/molecules27165204
Abstract: The neurotoxins methamphetamine (METH) and 1-methyl-4-phenylpyridinium (MPP+) damage catecholamine neurons. Although sharing the same mechanism to enter within these neurons, METH neurotoxicity mostly depends on oxidative species, while MPP+ toxicity depends on the inhibition of… read more here.
Keywords: induced mpp; microscopy; protects neurotoxicity; bacopa protects ... See more keywords