Extracellular Glutamate-Induced mTORC1 Activation via the IR/IRS/PI3K/Akt Pathway Enhances the Expansion of Porcine Intestinal Stem Cells.
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DOI: 10.1021/acs.jafc.9b03626
Abstract: Glutamate (Glu) is a critical nutritional regulator of intestinal epithelial homeostasis. In addition, intestinal stem cells (ISCs) at crypt bases are known to play important roles in maintaining the renewal and homeostasis of the intestinal… read more here.
Keywords: induced mtorc1; expansion; pi3k akt; glu ... See more keywords