Inhaled mRNA Nanoformulation with Biogenic Ribosomal Protein Reverses Established Pulmonary Fibrosis in a Bleomycin‐Induced Murine Model
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DOI: 10.1002/adma.202107506
Abstract: Idiopathic pulmonary fibrosis (IPF), a lethal respiratory disease with few treatment options, occurs due to repetitive microinjuries to alveolar epithelial cells (AECs) and progresses with an overwhelming deposition of extracellular matrix (ECM), ultimately resulting in… read more here.
Keywords: ribosomal protein; bleomycin induced; pulmonary fibrosis; mrna nanoformulation ... See more keywords
The prevention of latanoprost on osteoclastgenesis in vitro and lipopolysaccharide‐induced murine calvaria osteolysis in vivo
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DOI: 10.1002/jcb.26646
Abstract: Identification of agents that inhibit osteoclast formation and function is important for the treatment of osteolytic diseases which feature excessive osteoclast formation and bone resorption. Latanoprost (LTP), an analog of prostaglandin F2α, is a medication… read more here.
Keywords: calvaria osteolysis; lipopolysaccharide induced; induced murine; murine calvaria ... See more keywords
Erratum to Clinoptilolite in Dextran Sulphate Sodium-Induced Murine Colitis: Efficacy and Safety of a Microparticulate Preparation
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DOI: 10.1093/ibd/izy036
Abstract: Erratum to Clinoptilolite in Dextran Sulphate Sodium-Induced Murine Colitis: Efficacy and Safety of a Microparticulate Preparation On page 57, the final levels of lead, barium, manganese, and arsenic should have read as follows: 2.23 ±… read more here.
Keywords: sulphate sodium; murine colitis; clinoptilolite dextran; dextran sulphate ... See more keywords
Resveratrol decreases CD45+CD206− subtype macrophages in LPS‐induced murine acute lung injury by SOCS3 signalling pathway
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DOI: 10.1111/jcmm.14680
Abstract: Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) are life‐threatening condition in critically ill patients. Resveratrol (Res), a natural polyphenol, has therapeutic effect in animal model with ALI; however, whether Res attenuates ALI through modulation of… read more here.
Keywords: lps induced; cd206 subtype; cd45 cd206; induced murine ... See more keywords
Resolution of bleomycin-induced murine pulmonary fibrosis via a splenic lymphocyte subpopulation
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DOI: 10.1186/s12931-018-0783-2
Abstract: BackgroundIdiopathic pulmonary fibrosis (IPF) is a progressive disease with high mortality, and the pathogenesis of the disease is still incompletely understood. Although lymphocytes, especially CD4+CD25+FoxP3+ regulatory T cells (Tregs), have been implicated in the development… read more here.
Keywords: fibrosis; blm induced; murine pulmonary; pulmonary fibrosis ... See more keywords