A3G‐induced mutations show a low prevalence and exhibit plus‐strand regional distribution in hepatitis B virus DNA from patients with non‐hepatocellular carcinoma (HCC) and HCC
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical Virology"
DOI: 10.1002/jmv.26418
Abstract: APOBEC3G (A3G) cytidine deaminase is an innate immune restriction factor that can edit and inhibit hepatitis B virus (HBV) replication. The preferred target of A3G is deamination of the third cytosine of 5′CCC to form… read more here.
Keywords: induced mutations; hcc; dna; a3g induced ... See more keywords
Biological and prognostic impact of APOBEC-induced mutations in the spectrum of plasma cell dyscrasias and multiple myeloma cell lines
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DOI: 10.1038/leu.2017.345
Abstract: Biological and prognostic impact of APOBEC-induced mutations in the spectrum of plasma cell dyscrasias and multiple myeloma cell lines read more here.
Keywords: induced mutations; apobec induced; biological prognostic; impact apobec ... See more keywords
Probability of phenotypically detectable protein damage by ENU-induced mutations in the Mutagenetix database
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DOI: 10.1038/s41467-017-02806-4
Abstract: Computational inference of mutation effects is necessary for genetic studies in which many mutations must be considered as etiologic candidates. Programs such as PolyPhen-2 predict the relative severity of damage caused by missense mutations, but… read more here.
Keywords: protein; induced mutations; probability; enu induced ... See more keywords
A TILLING by sequencing approach to identify induced mutations in sunflower genes
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DOI: 10.1038/s41598-021-89237-w
Abstract: The Targeting Induced Local Lesions in Genomes (TILLING) technology is a reverse genetic strategy broadly applicable to every kind of genome and represents an attractive tool for functional genomic and agronomic applications. It consists of… read more here.
Keywords: induced mutations; approach identify; sequencing approach; identify induced ... See more keywords
Functional analysis of the ABCs of eye color in Helicoverpa armigera with CRISPR/Cas9-induced mutations
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DOI: 10.1038/srep40025
Abstract: Many insect pigments are localized in subcellular pigment granules, and transport of pigment precursors from the cytoplasm is accomplished by ABC proteins. Drosophila melanogaster has three half-transporter genes (white, scarlet, and brown, all affecting eye… read more here.
Keywords: induced mutations; helicoverpa armigera; crispr cas9; cas9 induced ... See more keywords