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   Articles with "induced mutations" as a keyword



Non‐Random Distribution of EMS‐Induced Mutations Reveals Preference for Open Chromatin and Expressed Genes in Rice

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recommendations! Published in 2025 at "Advanced Science"

DOI: 10.1002/advs.202510034

Abstract: Mutagenesis is an effective strategy to generate genetic resources for functional genomics and crop improvement. It is widely accepted that chemical‐induced mutations are randomly distributed across the genome. However, the randomness of such mutations remains… read more here.

Keywords: open chromatin; induced mutations; ems induced; expressed genes ... See more keywords
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A3G‐induced mutations show a low prevalence and exhibit plus‐strand regional distribution in hepatitis B virus DNA from patients with non‐hepatocellular carcinoma (HCC) and HCC

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recommendations! Published in 2020 at "Journal of Medical Virology"

DOI: 10.1002/jmv.26418

Abstract: APOBEC3G (A3G) cytidine deaminase is an innate immune restriction factor that can edit and inhibit hepatitis B virus (HBV) replication. The preferred target of A3G is deamination of the third cytosine of 5′CCC to form… read more here.

Keywords: induced mutations; hcc; dna; a3g induced ... See more keywords

Biological and prognostic impact of APOBEC-induced mutations in the spectrum of plasma cell dyscrasias and multiple myeloma cell lines

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recommendations! Published in 2018 at "Leukemia"

DOI: 10.1038/leu.2017.345

Abstract: Biological and prognostic impact of APOBEC-induced mutations in the spectrum of plasma cell dyscrasias and multiple myeloma cell lines read more here.

Keywords: induced mutations; apobec induced; biological prognostic; impact apobec ... See more keywords

Probability of phenotypically detectable protein damage by ENU-induced mutations in the Mutagenetix database

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recommendations! Published in 2017 at "Nature Communications"

DOI: 10.1038/s41467-017-02806-4

Abstract: Computational inference of mutation effects is necessary for genetic studies in which many mutations must be considered as etiologic candidates. Programs such as PolyPhen-2 predict the relative severity of damage caused by missense mutations, but… read more here.

Keywords: protein; induced mutations; probability; enu induced ... See more keywords

A TILLING by sequencing approach to identify induced mutations in sunflower genes

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recommendations! Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-89237-w

Abstract: The Targeting Induced Local Lesions in Genomes (TILLING) technology is a reverse genetic strategy broadly applicable to every kind of genome and represents an attractive tool for functional genomic and agronomic applications. It consists of… read more here.

Keywords: induced mutations; approach identify; sequencing approach; identify induced ... See more keywords

Functional analysis of the ABCs of eye color in Helicoverpa armigera with CRISPR/Cas9-induced mutations

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recommendations! Published in 2017 at "Scientific Reports"

DOI: 10.1038/srep40025

Abstract: Many insect pigments are localized in subcellular pigment granules, and transport of pigment precursors from the cytoplasm is accomplished by ABC proteins. Drosophila melanogaster has three half-transporter genes (white, scarlet, and brown, all affecting eye… read more here.

Keywords: induced mutations; helicoverpa armigera; crispr cas9; cas9 induced ... See more keywords

APOBEC-1 cofactors regulate APOBEC3-induced mutations in hepatitis B virus

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recommendations! Published in 2025 at "Journal of Virology"

DOI: 10.1128/jvi.01879-24

Abstract: ABSTRACT APOBEC3 proteins (A3s) play an important role in host innate immunity against viruses and DNA mutations in cancer. A3s-induced mutations in both viral and human DNA genomes vary significantly from non-lethal mutations in viruses… read more here.

Keywords: cancer; mutational activity; induced mutations; mutation ... See more keywords

MUTACLASH: Identifying functional small RNA target sites using crosslinking-induced mutations.

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recommendations! Published in 2025 at "RNA"

DOI: 10.1261/rna.080482.125

Abstract: Small RNAs play essential roles in gene regulation across diverse biological processes. Crosslinking, ligation, and sequencing of hybrids (CLASH) experiments have revealed that PIWI and Argonaute proteins can each bind a wide range of mRNA… read more here.

Keywords: crosslinking induced; small rna; induced mutations; target ... See more keywords