Trilaciclib prior to chemotherapy reduces the usage of supportive care interventions for chemotherapy‐induced myelosuppression in patients with small cell lung cancer: Pooled analysis of three randomized phase 2 trials
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Medicine"
DOI: 10.1002/cam4.4089
Abstract: Supportive care interventions used to manage chemotherapy‐induced myelosuppression (CIM), including granulocyte colony‐stimulating factors (G‐CSFs), erythropoiesis‐stimulating agents (ESAs), and red blood cell (RBC) transfusions, are burdensome to patients and associated with greater costs to health care… read more here.
Keywords: supportive care; care interventions; chemotherapy induced; induced myelosuppression ... See more keywords
Danggui Buxue Decoction enhances the anticancer activity of gemcitabine and alleviates gemcitabine-induced Myelosuppression.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2021.113965
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Danggui Buxue Decoction (DBD) as a traditional Chinese medicine (TCM) has been widely used to treat blood deficiency. With the immune regulation and hematopoietic effect, DBD improved the quality of life in non-small-cell… read more here.
Keywords: gem; gemcitabine; gem induced; induced myelosuppression ... See more keywords
Genetic Polymorphisms of Drug-Metabolizing Enzymes Involved in 6-Mercaptopurine-Induced Myelosuppression in Thai Pediatric Acute Lymphoblastic Leukemia Patients.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pediatric genetics"
DOI: 10.1055/s-0040-1715818
Abstract: Genetic polymorphisms of thiopurine S-methyltransferase (TPMT) and nucleoside diphosphate-linked moiety X-type motif 15 ( NUDT15 ) genes have been proposed as key determinants of 6-mercaptopurine (6-MP)-induced myelosuppression in pediatric acute lymphoblastic leukemia (ALL). In the… read more here.
Keywords: genetic polymorphisms; thai pediatric; mercaptopurine induced; induced myelosuppression ... See more keywords
Nucleosides and amino acids, isolated from Cordyceps sinensis, protected against cyclophosphamide-induced myelosuppression in mice
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DOI: 10.1080/14786419.2022.2043307
Abstract: Abstract The material basis of Cordyceps sinensis (Berk.) Sacc has not yet been well understood and natural C. sinensis resources are very rare. The present study aimed to clarify the substance basis and compare the… read more here.
Keywords: nucleosides amino; amino acids; induced myelosuppression; myelosuppression mice ... See more keywords
NUDT15 polymorphism and severe azathioprine‐induced myelosuppression in a Chinese man with pemphigus vulgaris
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Dermatology"
DOI: 10.1111/bjd.15840
Abstract: DEAR EDITOR, Pemphigus vulgaris (PV) is a life-threatening autoimmune mucocutaneous disease with formidable treatment challenges. Since the first report of successful treatment of PV in 1969 with azathioprine (AZA), which was originally used to treat… read more here.
Keywords: pemphigus vulgaris; dermatology; myelosuppression; thiopurine induced ... See more keywords
Pharmacological Role of Capparis decidua (Forssk.) Edgew in Preventing Cyclophosphamide-induced Myelosuppression and Modulating Innate and Adaptive Immune Response
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DOI: 10.1177/15593258221123672
Abstract: Background Capparis decidua (Forssk.) Edgew is reported to be practiced in the traditional system of medicine for the management of various immunological pathologies. Purpose The current study was designed to evaluate the modulatory effects of… read more here.
Keywords: induced myelosuppression; decidua; decidua forssk; capparis decidua ... See more keywords
Jian-Pi-Bu-Xue-Formula Alleviates Cyclophosphamide-Induced Myelosuppression via Up-Regulating NRF2/HO1/NQO1 Signaling
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.01302
Abstract: Jian-pi-bu-xue-formula (JPBXF), a TCM formula composed of twelve Chinese medicinal herbs, has been used in clinic to ease patients’ state of weakness and fatigue especially after receiving anti-tumor chemotherapy in China. The lack of the… read more here.
Keywords: induced myelosuppression; ho1 nqo1; ctx induced; jpbxf ... See more keywords
Ayurveda-based Botanicals as Therapeutic Adjuvants in Paclitaxel-induced Myelosuppression
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DOI: 10.3389/fphar.2022.835616
Abstract: Chemotherapy-induced myelosuppression is one of the major challenges in cancer treatment. Ayurveda-based immunomodulatory botanicals Asparagus racemosus Willd (AR/Shatavari) and Withania somnifera (L.). Dunal (WS/Ashwagandha) have potential role to manage myelosuppression. We have developed a method… read more here.
Keywords: therapeutic adjuvants; induced myelosuppression; ptx; myelosuppression ... See more keywords
Development of a Machine Learning-Based Prediction Model for Chemotherapy-Induced Myelosuppression in Children with Wilms’ Tumor
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DOI: 10.3390/cancers15041078
Abstract: Simple Summary Wilms’ tumor is the most common renal malignant tumor in children, and chemotherapy is an indispensable part of the treatment for most Wilms’ tumor patients. Chemotherapy-induced myelosuppression is the most common and serious… read more here.
Keywords: chemotherapy induced; induced myelosuppression; model; tumor ... See more keywords
Hematopoietic Effects of Angelica gigas Nakai Extract on Cyclophosphamide-Induced Myelosuppression
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DOI: 10.3390/plants11243476
Abstract: Myelosuppression is a major adverse effect of chemotherapy. With the increasing number of cancer patients worldwide, there is a growing interest in therapeutic approaches that reduce the adverse effects of chemotherapy. Angelica gigas Nakai (AGN)… read more here.
Keywords: induced myelosuppression; angelica gigas; myelosuppression; gigas nakai ... See more keywords