Evaluation of Autoantibody Binding to Cardiac Tissue in Multisystem Inflammatory Syndrome in Children and COVID-19 Vaccination–Induced Myocarditis
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.14291
Abstract: Key Points Question Do autoantibodies targeting the heart play a role in the cardiac complications of SARS-CoV-2–associated multisystem inflammatory syndrome in children (MIS-C) or COVID-19 mRNA vaccination? Findings This diagnostic study including 20 children with… read more here.
Keywords: induced myocarditis; inflammatory syndrome; syndrome children; multisystem inflammatory ... See more keywords
Expansion of CD11b+Ly‐6C+ myeloid‐derived suppressor cells (MDSCs) driven by galectin‐9 attenuates CVB3‐induced myocarditis
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Immunology"
DOI: 10.1016/j.molimm.2017.01.013
Abstract: &NA; Galectin‐9 is known to play a role in the modulation of innate and adaptive immunity to ameliorate CVB3‐induced myocarditis. In the present study, we found that galectin‐9 induced the expansion of CD11b+Ly‐6C+ myeloid‐derived suppressor… read more here.
Keywords: expansion cd11b; cvb3 induced; induced myocarditis; cd11b ... See more keywords
Vaccine-Induced Myocarditis in Two Intern Doctors in the Same Night Shift
Sign Up to like & getrecommendations! Published in 2022 at "Prehospital and Disaster Medicine"
DOI: 10.1017/s1049023x22001078
Abstract: Abstract The coronavirus disease 2019 (COVID-19) pandemic has affected millions of people around the globe and vaccines against the disease have started to develop. Side effects of the vaccine have been reported in the literature,… read more here.
Keywords: myocarditis; induced myocarditis; myocarditis two; vaccine induced ... See more keywords
Gasdermin-E-mediated pyroptosis drives immune checkpoint inhibitor-associated myocarditis via cGAS-STING activation
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-50996-5
Abstract: Immune checkpoint inhibitor (ICI)-induced myocarditis involves intensive immune/inflammation activation; however, its molecular basis is unclear. Here, we show that gasdermin-E (GSDME), a gasdermin family member, drives ICI-induced myocarditis. Pyroptosis mediated by GSDME, but not the… read more here.
Keywords: activation; ici induced; induced myocarditis; myocarditis ... See more keywords
COVID‐19 vaccine induced myocarditis in young males: A systematic review
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Clinical Investigation"
DOI: 10.1111/eci.13947
Abstract: Myocarditis is a rare but significant adverse event associated with COVID‐19 vaccination, especially for men under 40. If the risk of myocarditis is not stratified by pertinent risk factors, it may be diluted for high‐risk… read more here.
Keywords: myocarditis; induced myocarditis; vaccine induced; risk ... See more keywords
New drugs and new toxicities: pembrolizumab-induced myocarditis
Sign Up to like & getrecommendations! Published in 2018 at "BMJ Case Reports"
DOI: 10.1136/bcr-2017-223252
Abstract: Pembrolizumab is an immune checkpoint inhibitor that significantly improves clinical outcomes in numerous solid organ malignancies. Despite successful therapeutic responses, this new drug comes with a constellation of adverse reactions. Herein, we chronicle the case… read more here.
Keywords: toxicities pembrolizumab; new toxicities; induced myocarditis; pembrolizumab induced ... See more keywords
Clenbuterol-induced myocarditis in a young man desiring to lose weight
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Case Reports"
DOI: 10.1136/bcr-2021-247898
Abstract: A young man in his late 20s was presented with acute chest pain, concave ST elevation in lateral and inferior leads on ECG and elevated cardiac troponin. A thorough clinical history was notable for clenbuterol… read more here.
Keywords: man; clenbuterol induced; young man; induced myocarditis ... See more keywords
Paclitaxel-induced myocarditis presenting as new-onset heart failure
Sign Up to like & getrecommendations! Published in 2024 at "BMJ Case Reports"
DOI: 10.1136/bcr-2023-255646
Abstract: Myocarditis with systolic dysfunction is not typically associated with paclitaxel use. Here, we present a case of paclitaxel-induced myocarditis with systolic dysfunction developing after two cycles of carboplatin/paclitaxel in a woman with uterine papillary serous… read more here.
Keywords: paclitaxel; paclitaxel induced; induced myocarditis; heart failure ... See more keywords
Nicotinic Agonist Inhibits Cardiomyocyte Apoptosis in CVB3-Induced Myocarditis via α3β4-nAChR/PI3K/Akt-Dependent Survivin Upregulation
Sign Up to like & getrecommendations! Published in 2019 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2019/9496419
Abstract: Background Cardiomyocyte apoptosis is critical for the development of coxsackievirus B3- (CVB3-) induced myocarditis, which is a common cardiac disease that may result in heart failure or even sudden death. Previous studies have associated CVB3-induced… read more here.
Keywords: cvb3 induced; apoptosis; survivin; induced myocarditis ... See more keywords
Neurogenic differentiation 2 promotes inflammatory activation of macrophages in doxorubicin-induced myocarditis via regulating protein kinase D
Sign Up to like & getrecommendations! Published in 2025 at "BMC Cardiovascular Disorders"
DOI: 10.1186/s12872-025-04626-7
Abstract: Although it has been established that protein kinase D (PKD) plays a crucial role in various diseases, its precise role in myocarditis remains elusive. To investigate PKD’s involvement in myocarditis, we established a mouse model… read more here.
Keywords: protein kinase; induced myocarditis; heart tissues; pkd ... See more keywords
Isolated nausea and vomiting as the cardinal presenting symptoms of clozapine-induced myocarditis: a case report
Sign Up to like & getrecommendations! Published in 2020 at "BMC Psychiatry"
DOI: 10.1186/s12888-020-02955-9
Abstract: Background Clozapine is an atypical antipsychotic proven to be superior in the treatment of treatment-resistant schizophrenia. Myocarditis is a rare, but well-known complication of treatment with clozapine. Only few cases have been reported in which… read more here.
Keywords: clozapine induced; induced myocarditis; case; nausea vomiting ... See more keywords