Validation of different personalized risk models of chemotherapy‐induced nausea and vomiting: results of a randomized, double‐blind, phase III trial of fosaprepitant for cancer patients treated with high‐dose cisplatin
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DOI: 10.1002/cac2.12397
Abstract: Highly emetogenic chemotherapy induces emesis in cancer patients without prophylaxis. The purpose of this study was to evaluate the efficacy and safety of a fosaprepitant‐based triple antiemetic regimen for the prevention of chemotherapy‐induced nausea and… read more here.
Keywords: induced nausea; chemotherapy induced; cancer patients; risk ... See more keywords
Acupuncture for the prevention of chemotherapy-induced nausea and vomiting in cancer patients: A systematic review and meta-analysis.
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DOI: 10.1002/cam4.5962
Abstract: PURPOSE To assess the effectiveness and safety of acupuncture for the prevention of chemotherapy-induced nausea and vomiting (CINV), with a specific intention on exploring sources of between-study variation in treatment effects. METHODS MEDLINE, EMBASE, Cochrane… read more here.
Keywords: induced nausea; chemotherapy induced; acupuncture; prevention chemotherapy ... See more keywords
Netupitant-palonosetron to prevent chemotherapy-induced nausea and vomiting in multiple myeloma patients receiving high-dose melphalan and autologous stem cell transplantation
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DOI: 10.1007/s00277-020-04180-6
Abstract: Dear Editor, Chemotherapy-induced nausea and vomiting (CINV) can be associated with reduced quality of life and meaningful complications in multiple myeloma (MM) patients receiving high-dose (HD)-melphalan followed by autologous stem cell transplantation (ASCT) [1, 2].… read more here.
Keywords: chemotherapy; patients receiving; induced nausea; chemotherapy induced ... See more keywords
Prevention of chemotherapy-induced nausea: the role of neurokinin-1 (NK1) receptor antagonists
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DOI: 10.1007/s00520-017-3585-z
Abstract: Chemotherapy-induced nausea (CIN) has a significant negative impact on the quality of life of cancer patients. The use of 5-hydroxytryptamine-3 (5-HT3) receptor antagonists (RAs) has reduced the risk of vomiting, but (except for palonosetron) their… read more here.
Keywords: chemotherapy; nausea; induced nausea; chemotherapy induced ... See more keywords
Should palonosetron be a preferred 5-HT3 receptor antagonist for chemotherapy-induced nausea and vomiting? An updated systematic review and meta-analysis
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DOI: 10.1007/s00520-018-4237-7
Abstract: PurposeChemotherapy-induced nausea and vomiting (CINV) continues to be a common side effect of systemic anticancer therapy, decreasing quality of life and increasing resource utilization. The aim of this meta-analysis was to investigate the comparative efficacy… read more here.
Keywords: induced nausea; nausea vomiting; palonosetron; meta analysis ... See more keywords
ASCO, NCCN, MASCC/ESMO: a comparison of antiemetic guidelines for the treatment of chemotherapy-induced nausea and vomiting in adult patients
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DOI: 10.1007/s00520-018-4464-y
Abstract: Chemotherapy-induced nausea and vomiting (CINV) is a common toxicity that may impair the quality of life of patients with a variety of early- and end-stage malignancies. In light of recent changes in the optimal management… read more here.
Keywords: esmo; induced nausea; chemotherapy induced; mascc esmo ... See more keywords
Prevention of chemotherapy-induced nausea and vomiting after high-dose melphalan and stem cell transplantation: review of the evidence and suggestions
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DOI: 10.1007/s00520-018-4594-2
Abstract: IntroductionHigh-dose melphalan (HDMel) is the most common conditioning chemotherapy regimen for autologous stem cell transplantation (SCT) in patients affected by multiple myeloma (MM). No consensus exists for the emetogenicity or prophylaxis of chemotherapy-induced nausea and… read more here.
Keywords: chemotherapy; cell transplantation; dose melphalan; stem cell ... See more keywords
Evaluation of Adherence to Antiemetic Treatment Guidelines in Patients With Chemotherapy-Induced Nausea and Vomiting in Teaching Hospitals in Tehran
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DOI: 10.1007/s13187-020-01689-2
Abstract: The present study evaluated adherence to antiemetic guidelines for prevention and treatment of chemotherapy-induced nausea and vomiting (CINV) in four tertiary university teaching hospitals in Tehran. This prospective observational study enrolled 382 adult patients on… read more here.
Keywords: category; adherence antiemetic; induced nausea; cinv ... See more keywords
Evaluating Aprepitant single-dose plus granisetron and dexamethasone in children receiving highly emetogenic chemotherapy for the prevention of chemotherapy-induced nausea and vomiting: A triple-blinded randomized clinical trial.
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DOI: 10.1016/j.htct.2022.02.004
Abstract: INTRODUCTION This study was performed to evaluate the degree of 3-day chemotherapy-induced nausea and vomiting (CINV) in children with cancer who received highly emetogenic chemotherapy (HEC) to ascertain the efficacy of aprepitant single-dose on dayL… read more here.
Keywords: chemotherapy; single dose; chemotherapy induced; day ... See more keywords
Risk Factors Associated With Chemotherapy-Induced Nausea in the Week Before the Next Cycle and Impact of Nausea on Quality of Life Outcomes.
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DOI: 10.1016/j.jpainsymman.2018.05.019
Abstract: CONTEXT Despite current advances in antiemetic treatments, between 19% and 58% of oncology patients experience chemotherapy-induced nausea (CIN). OBJECTIVES Aims of this post hoc exploratory analysis were to determine occurrence, severity, and distress of CIN… read more here.
Keywords: cin; factors associated; induced nausea; stress ... See more keywords
Alterations in Patterns of Gene Expression and Perturbed Pathways in the Gut-Brain Axis Are Associated With Chemotherapy-Induced Nausea.
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DOI: 10.1016/j.jpainsymman.2019.12.352
Abstract: CONTEXT Despite current advances in antiemetic treatments, approximately 50% of oncology patients experience chemotherapy-induced nausea (CIN). OBJECTIVES The purpose of this study was to evaluate for differentially expressed genes and perturbed pathways associated with the… read more here.
Keywords: cin; perturbed pathways; induced nausea; chemotherapy induced ... See more keywords