Differences in the sensitivity of classically and alternatively activated macrophages to TAK1 inhibitor-induced necroptosis
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-020-02623-7
Abstract: Controlling the balance of pro-inflammatory M1 versus anti-inflammatory M2 macrophages may have paramount therapeutic benefit in cardiovascular diseases, infections, cancer and chronic inflammation. The targeted depletion of different macrophage populations provides a therapeutic option to… read more here.
Keywords: inhibitor induced; inhibitor; induced necroptosis; sensitivity ... See more keywords
Cisplatin-induced necroptosis in TNFα dependent and independent pathways.
Sign Up to like & getrecommendations! Published in 2017 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2017.01.004
Abstract: Cisplatin is a chemotherapeutic drug for treatment of many solid tumors. It has been shown to induce apoptosis and/or necrosis in different types of cancer cells. However, the underlying mechanisms remain elusive. In this study,… read more here.
Keywords: necroptosis tnf; cisplatin; induced necroptosis; cisplatin induced ... See more keywords
Opposite Effects of Apoptotic and Necroptotic Cellular Pathways on Rotavirus Replication
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DOI: 10.1128/jvi.01222-21
Abstract: Viral infection usually culminates in cell death through apoptosis, necroptosis, and, rarely, pyroptosis. Necroptosis is a form of programmed necrosis that is mediated by signaling complexes of the receptor-interacting protein kinase 1 (RIPK1), RIPK3, and… read more here.
Keywords: induced necroptosis; ripk1; apoptosis; rva ... See more keywords