A human relevant mixture of persistent organic pollutants (POPs) and perfluorooctane sulfonic acid (PFOS) enhance nerve growth factor (NGF)-induced neurite outgrowth in PC12 cells.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2020.12.007
Abstract: Disruption of neurite outgrowth is a marker for neurotoxicity. Persistent organic pollutants (POPs) are potential developmental neurotoxicants. We investigated their effect on neurite outgrowth in PC12 rat pheochromocytoma cells, in absence or presence of nerve… read more here.
Keywords: induced neurite; ngf induced; pfos; neurite outgrowth ... See more keywords
Atlastin regulates store-operated calcium entry for nerve growth factor-induced neurite outgrowth
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DOI: 10.1038/srep43490
Abstract: Homotypic membrane fusion of the endoplasmic reticulum (ER) is mediated by a class of dynamin-like GTPases known as atlastin (ATL). Depletion of or mutations in ATL cause an unbranched ER morphology and hereditary spastic paraplegia… read more here.
Keywords: store operated; nerve growth; induced neurite; outgrowth ... See more keywords
Propionate Protects Haloperidol-Induced Neurite Lesions Mediated by Neuropeptide Y
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DOI: 10.3389/fnins.2018.00743
Abstract: Haloperidol is a commonly used antipsychotic drug for treating schizophrenia. Clinical imaging studies have found that haloperidol can cause volume loss of human brain tissue, which is supported by animal studies showing that haloperidol reduces… read more here.
Keywords: haloperidol induced; induced neurite; propionate; effect ... See more keywords
OMICS Analyses Unraveling Related Gene and Protein-Driven Molecular Mechanisms Underlying PACAP 38-Induced Neurite Outgrowth in PC12 Cells
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DOI: 10.3390/ijms24044169
Abstract: The study aimed to understand mechanism/s of neuronal outgrowth in the rat adrenal-derived pheochromocytoma cell line (PC12) under pituitary adenylate cyclase-activating polypeptide (PACAP) treatment. Neurite projection elongation was suggested to be mediated via Pac1 receptor-mediated… read more here.
Keywords: induced neurite; pacap induced; pacap; gene protein ... See more keywords