The role of glial cells in Zika virus-induced neurodegeneration.
Sign Up to like & getrecommendations! Published in 2023 at "Glia"
DOI: 10.1002/glia.24353
Abstract: Zika virus (ZIKV) is a strongly neurotropic flavivirus whose infection has been associated with microcephaly in neonates. However, clinical and experimental evidence indicate that ZIKV also affects the adult nervous system. In this regard, in… read more here.
Keywords: induced neurodegeneration; glial cells; zikv; nervous system ... See more keywords
Neuroprotective effect of damaurone D in a C. elegans model of Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2021 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2021.135623
Abstract: In this study, we evaluated the protective effects of damaurone D (DaD), a dihydropyranoaurone compound, on dopaminergic (DA) neurodegeneration in Caenorhabditis elegans. The results showed that DaD treatment could successfully increase the survival rate of… read more here.
Keywords: neuroprotective effect; induced neurodegeneration; dad; parkinson disease ... See more keywords
NADPH oxidase contributes to streptozotocin-induced neurodegeneration
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2017.06.050
Abstract: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the progressive loss of memory. The neurodegeneration induced by AD has been linked to oxidative damage. However, little is known about the involvement of NADPH oxidase… read more here.
Keywords: stz; neurodegeneration; induced neurodegeneration; mice ... See more keywords
Lactate Supply from Astrocytes to Neurons and its Role in Ischemic Stroke-induced Neurodegeneration
Sign Up to like & getrecommendations! Published in 2022 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2021.11.035
Abstract: Glucose transported to the brain is metabolized to lactate in astrocytes and supplied to neuronal cells via a monocarboxylic acid transporter (MCT). Lactate is used in neuronal cells for various functions, including learning and memory… read more here.
Keywords: induced neurodegeneration; lactate; lactate supply; stroke ... See more keywords
Profiling Secreted miRNA Biomarkers of Chemical-Induced Neurodegeneration in Human iPSC-Derived Neurons
Sign Up to like & getrecommendations! Published in 2022 at "Toxicological Sciences"
DOI: 10.1093/toxsci/kfac011
Abstract: Abstract Elucidation of predictive fluidic biochemical markers to detect and monitor chemical-induced neurodegeneration has been a major challenge due to a lack of understanding of molecular mechanisms driving altered neuronal morphology and function, as well… read more here.
Keywords: derived neurons; chemical induced; biomarkers chemical; induced neurodegeneration ... See more keywords
Synthesis, In Silico and Pharmacological Evaluation of New Thiazolidine-4-Carboxylic Acid Derivatives Against Ethanol-Induced Neurodegeneration and Memory Impairment
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s357082
Abstract: Introduction Several studies revealed that alcohol utilization impairs memory in adults; however, the underlying mechanism is still unclear. The production of inflammatory markers and reactive oxygen species (ROS) plays a major role in neurodegeneration, which… read more here.
Keywords: new thiazolidine; ethanol induced; induced neurodegeneration; memory impairment ... See more keywords
Duloxetine by Modulating the Akt/GSK3 Signaling Pathways Has Neuroprotective Effects against Methamphetamine-Induced Neurodegeneration and Cognition Impairment in Rats
Sign Up to like & getrecommendations! Published in 2019 at "Iranian Journal of Medical Sciences"
DOI: 10.30476/ijms.2019.44515
Abstract: Background: The neuroprotective effects of duloxetine, as an antidepressant agent, and the neurodegenerative effects of methamphetamine have been shown in previous studies. Nonetheless, their exact neurochemical and behavioral effects are still unclear. In the current… read more here.
Keywords: induced neurodegeneration; effects methamphetamine; akt gsk3; methamphetamine induced ... See more keywords
Bromodomains in Human-Immunodeficiency Virus-Associated Neurocognitive Disorders: A Model of Ferroptosis-Induced Neurodegeneration
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.904816
Abstract: Human immunodeficiency virus (HIV)-associated neurocognitive disorders (HAND) comprise a group of illnesses marked by memory and behavioral dysfunction that can occur in up to 50% of HIV patients despite adequate treatment with combination antiretroviral drugs.… read more here.
Keywords: immunodeficiency virus; induced neurodegeneration; ferroptosis; human immunodeficiency ... See more keywords