Articles with "induced neuropathy" as a keyword



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Prognostic value of cutaneous reinnervation with GAP-43 in oxaliplatin-induced neuropathy

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Published in 2022 at "Journal of Neurology"

DOI: 10.1007/s00415-022-11035-9

Abstract: Oxaliplatin-induced neuropathy (OIN) implies axonal damage of both small and large sensory nerve fibers. We aimed at comparing the neurophysiological changes occurred after treatment and the capability to recovery based on histological marker of re-innervation… read more here.

Keywords: induced neuropathy; oxaliplatin induced; gap; treatment ... See more keywords
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1865 Preventative and Therapeutic Effects of Low-Temperature Atmospheric-Pressure Plasma in a Mouse Model of Paclitaxel-Induced Neuropathy

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Published in 2019 at "Journal of Minimally Invasive Gynecology"

DOI: 10.1016/j.jmig.2019.09.249

Abstract: Study Objective Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of cancer treatment. No medication has been shown to be effective in the treatment of CIPN. Low temperature plasma (LTP) has proven to be… read more here.

Keywords: low temperature; paclitaxel induced; induced neuropathy; treatment ... See more keywords
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Nerve conduction, circulating osteopontin and taxane-induced neuropathy in breast cancer patients

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Published in 2020 at "Neurophysiologie Clinique"

DOI: 10.1016/j.neucli.2019.12.001

Abstract: OBJECTIVE Chemotherapy-induced peripheral neuropathy (CIPN) is a disabling complication related to taxanes. Underlying mechanisms are not completely understood and no specific treatment exists. We investigated the role of nerve conduction studies (NCS) and of serum… read more here.

Keywords: nerve conduction; induced neuropathy; taxane induced; breast cancer ... See more keywords
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First-in-Class Dual Hybrid Carbonic Anhydrase Inhibitors and Transient Receptor Potential Vanilloid 1 Agonists Revert Oxaliplatin-Induced Neuropathy

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Published in 2023 at "Journal of Medicinal Chemistry"

DOI: 10.1021/acs.jmedchem.2c01911

Abstract: Here, we report for the first time a series of compounds potentially useful for the management of oxaliplatin-induced neuropathy (OINP) able to modulate the human Carbonic Anhydrases (hCAs) as well as the Transient Receptor Potential… read more here.

Keywords: transient receptor; receptor potential; induced neuropathy; oxaliplatin induced ... See more keywords
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Otic Organoids Containing Spiral Ganglion Neuron-like Cells Derived from Human-induced Pluripotent Stem Cells as a Model of Drug-induced Neuropathy

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Published in 2022 at "Stem Cells Translational Medicine"

DOI: 10.1093/stcltm/szab023

Abstract: Abstract The spiral ganglion of the cochlea is essential for hearing and contains primary bipolar neurons that relay action potentials generated by mechanosensory hair cells. Injury to spiral ganglion neurons (SGNs) causes permanent hearing loss… read more here.

Keywords: otic organoids; induced neuropathy; spiral ganglion; like cells ... See more keywords
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Arsenic-Induced Neuropathy by Improper Use of Chinese Medicine: A Case Report.

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Published in 2018 at "American Journal of Therapeutics"

DOI: 10.1097/mjt.0000000000000576

Abstract: To the Editor: A 27-year-old Chinese man presented with numbness and weakness in glove-and-stocking distribution for 3 months. Physical examination showed reduced power of 4/5 over the extremities, generalized areflexia, and impaired proprioception and light… read more here.

Keywords: medicine; intake; use; induced neuropathy ... See more keywords
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An integrated perspective on diabetic, alcoholic, and drug-induced neuropathy, etiology, and treatment in the US

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Published in 2017 at "Journal of Pain Research"

DOI: 10.2147/jpr.s125987

Abstract: Neuropathic pain (NeuP) is a syndrome that results from damaged nerves and/or aberrant regeneration. Common etiologies of neuropathy include chronic illnesses and medication use. Chronic disorders, such as diabetes and alcoholism, can cause neuronal injury… read more here.

Keywords: etiology treatment; etiology; induced neuropathy; drug induced ... See more keywords
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Through Its Powerful Antioxidative Properties, L-Theanine Ameliorates Vincristine-Induced Neuropathy in Rats

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Published in 2023 at "Antioxidants"

DOI: 10.3390/antiox12040803

Abstract: L-theanine (LT), which is a major amino acid found in green tea, was shown to alleviate Vincristine (VCR)-induced peripheral neuropathy and associated neuronal functional changes in rats. To induce peripheral neuropathy, rats were administered VCR… read more here.

Keywords: powerful antioxidative; properties theanine; neuropathy rats; vcr induced ... See more keywords
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TENS Improves Cisplatin-Induced Neuropathy in Lung Cancer Patients

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Published in 2022 at "Medicina"

DOI: 10.3390/medicina58101405

Abstract: Background: Cisplatin-induced peripheral neuropathy is a common complication of cisplatin therapy, which develops in most patients with lung cancer. There are no effective preventive measures and once it occurs there is no effective therapy, except… read more here.

Keywords: cisplatin induced; lung cancer; induced neuropathy; tens therapy ... See more keywords
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Targeting Anti-Inflammatory Pathways to Treat Diabetes-Induced Neuropathy by 6-Hydroxyflavanone

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Published in 2023 at "Nutrients"

DOI: 10.3390/nu15112552

Abstract: It is evident that inflammation and metabolic syndrome instigated by diabetes mellitus can precipitate diabetes-induced neuropathy (DIN) and pain. In order to find an effective therapeutic method for diabetes-related problems, a multi-target-directed ligand model was… read more here.

Keywords: cox; hydroxyflavanone; induced neuropathy; anti inflammatory ... See more keywords
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Escinosomes: Safe and Successful Nanovesicles to Deliver Andrographolide by a Subcutaneous Route in a Mice Model of Oxaliplatin-Induced Neuropathy

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Published in 2022 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics14030493

Abstract: Andrographolide (AG) is a natural diterpene lactone endowed with considerable therapeutic potential for treating numerous diseases, including neurological disorders, but its low aqueous solubility and scarce bioavailability limit its clinical use. To overcome this problem,… read more here.

Keywords: oxaliplatin induced; model oxaliplatin; induced neuropathy; loaded escinosomes ... See more keywords