Unveiling predisposing factors for cefepime‐induced neurotoxicity: A systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2025 at "British Journal of Clinical Pharmacology"
DOI: 10.1002/bcp.70120
Abstract: The aim of this study was to elucidate the risk factors associated with the development of cefepime‐induced neurotoxicity (CIN). read more here.
Keywords: predisposing factors; cefepime induced; factors cefepime; unveiling predisposing ... See more keywords
Oxidative Stress and Apoptosis in Bisphenol AF–Induced Neurotoxicity in Zebrafish Embryos
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology and Chemistry"
DOI: 10.1002/etc.5412
Abstract: Bisphenol AF (BPAF) is a structural counterpart of bisphenol A that is utilized in the food and beverage industry. The present study investigated the potential mechanisms in BPAF‐induced neurotoxicity in zebrafish embryos. The BPAF concentrations… read more here.
Keywords: induced neurotoxicity; apoptosis; oxidative stress; zebrafish embryos ... See more keywords
Deletion of RE1‐silencing transcription factor in striatal astrocytes exacerbates manganese‐induced neurotoxicity in mice
Sign Up to like & getrecommendations! Published in 2022 at "Glia"
DOI: 10.1002/glia.24226
Abstract: Chronic manganese (Mn) overexposure causes a neurological disorder, referred to as manganism, exhibiting symptoms similar to parkinsonism. Dysfunction of the repressor element‐1 silencing transcription factor (REST) is associated with various neurodegenerative diseases such as Parkinson's… read more here.
Keywords: induced neurotoxicity; astrocytic rest; deletion; rest ... See more keywords
Three‐dimensional spheroid cell culture of human MSC‐derived neuron‐like cells: New in vitro model to assess magnetite nanoparticle‐induced neurotoxicity effects
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4292
Abstract: As nanoparticles (NPs) can access the brain and impact on CNS function, novel in vitro models for the evaluation of NPs‐induced neurotoxicity are advocated. Three‐dimensional spheroids of primary neuron‐like cells (hNLCs) of human origin have… read more here.
Keywords: cell; induced neurotoxicity; neuron like; three dimensional ... See more keywords
Melatonin is effective in attenuating cisplatin-induced neurotoxicity.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.23075
Abstract: Cisplatin (Cis) is a chemotherapeutic agent that has many side effects. Neurotoxicity is one of the most important of these side effects. Oxidative stress and neuroinflammation are the best-known mechanisms in the pathogenesis of neurotoxicity… read more here.
Keywords: vehicle; mel; cis; induced neurotoxicity ... See more keywords
GRIA1 Alleviates Sevoflurane‐Induced Neurotoxicity by Suppressing Autophagy
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.70281
Abstract: The neurotoxicity caused by inhaled anesthetics has attracted more attention. Sevoflurane (SEV), a common general anesthetic, has a wide range of clinical applications. However, the underlying molecular mechanism of SEV‐induced neurotoxicity is blurry.Cell viability and… read more here.
Keywords: neurotoxicity; suppressing autophagy; neurotoxicity suppressing; cell viability ... See more keywords
Daidzein Attenuates Cadmium‐Induced Neurotoxicity via Inhibiting Apoptosis and Mitophagy in the Cerebral Cortex of Sprague–Dawley Rats
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.70299
Abstract: Cadmium (Cd), a prevalent environmental pollutant, is of significant concern owing to its neurotoxicity; thus, the identification of effective interventions for nerve injury caused by Cd is crucial. Mitochondrial signaling pathway‐mediated apoptosis and PTEN‐induced putative… read more here.
Keywords: sprague dawley; cerebral cortex; induced neurotoxicity; apoptosis ... See more keywords
Protective effects of crocin against endogenous Aβ-induced neurotoxicity in N2a/APP695swe cells.
Sign Up to like & getrecommendations! Published in 2021 at "Psychopharmacology"
DOI: 10.1007/s00213-021-05899-4
Abstract: Alzheimer's disease (AD) is a most common neurodegenerative disorder worldwide. Because of its complex pathogenesis, the prevention and therapies of AD still are a severe challenge. Evidence suggested that crocin, the major component of saffron,… read more here.
Keywords: crocin endogenous; n2a app695swe; induced neurotoxicity; app695swe cells ... See more keywords
Mini review–vanadium-induced neurotoxicity and possible targets
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DOI: 10.1007/s10072-019-04188-5
Abstract: Vanadium, a transition metal, ubiquitous in nature is known to have therapeutic effect as well as toxic effect. It is known to possess antidiabetic, antitumor and antiparasitic activity. However, on long term exposure, it produces… read more here.
Keywords: possible targets; induced neurotoxicity; review; neurotoxicity ... See more keywords
From neurotoxicity to neuroprotection: Rethinking GABAAR-targeting anesthetics
Sign Up to like & getrecommendations! Published in 2025 at "Cell Biology and Toxicology"
DOI: 10.1007/s10565-025-10057-z
Abstract: The brain growth spurt (BGS) represents a pivotal window in neurodevelopment, defined by rapid neurogenesis, heightened synaptogenesis, and the dynamic establishment of neural networks. During this phase, heightened brain plasticity significantly enhances learning and memory… read more here.
Keywords: neurotoxicity; brain; susceptibility; anesthetic induced ... See more keywords
Neuroprotective effects of carvacrol against cadmium-induced neurotoxicity in rats: role of oxidative stress, inflammation and apoptosis.
Sign Up to like & getrecommendations! Published in 2022 at "Metabolic brain disease"
DOI: 10.1007/s11011-022-00945-2
Abstract: Cadmium (Cd), is a heavy metal reported to be associated with oxidative stress and inflammation. In this paper, we investigated the possible protective effects of carvacrol against Cd-induced neurotoxicity in rats. Adult male Sprague Dawley… read more here.
Keywords: effects carvacrol; oxidative stress; induced neurotoxicity; neurotoxicity ... See more keywords