Oxidative Stress and Apoptosis in Bisphenol AF–Induced Neurotoxicity in Zebrafish Embryos
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology and Chemistry"
DOI: 10.1002/etc.5412
Abstract: Bisphenol AF (BPAF) is a structural counterpart of bisphenol A that is utilized in the food and beverage industry. The present study investigated the potential mechanisms in BPAF‐induced neurotoxicity in zebrafish embryos. The BPAF concentrations… read more here.
Keywords: induced neurotoxicity; apoptosis; oxidative stress; zebrafish embryos ... See more keywords
Deletion of RE1‐silencing transcription factor in striatal astrocytes exacerbates manganese‐induced neurotoxicity in mice
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DOI: 10.1002/glia.24226
Abstract: Chronic manganese (Mn) overexposure causes a neurological disorder, referred to as manganism, exhibiting symptoms similar to parkinsonism. Dysfunction of the repressor element‐1 silencing transcription factor (REST) is associated with various neurodegenerative diseases such as Parkinson's… read more here.
Keywords: induced neurotoxicity; astrocytic rest; deletion; rest ... See more keywords
Three‐dimensional spheroid cell culture of human MSC‐derived neuron‐like cells: New in vitro model to assess magnetite nanoparticle‐induced neurotoxicity effects
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4292
Abstract: As nanoparticles (NPs) can access the brain and impact on CNS function, novel in vitro models for the evaluation of NPs‐induced neurotoxicity are advocated. Three‐dimensional spheroids of primary neuron‐like cells (hNLCs) of human origin have… read more here.
Keywords: cell; induced neurotoxicity; neuron like; three dimensional ... See more keywords
Melatonin is effective in attenuating cisplatin-induced neurotoxicity.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.23075
Abstract: Cisplatin (Cis) is a chemotherapeutic agent that has many side effects. Neurotoxicity is one of the most important of these side effects. Oxidative stress and neuroinflammation are the best-known mechanisms in the pathogenesis of neurotoxicity… read more here.
Keywords: vehicle; mel; cis; induced neurotoxicity ... See more keywords
Protective effects of crocin against endogenous Aβ-induced neurotoxicity in N2a/APP695swe cells.
Sign Up to like & getrecommendations! Published in 2021 at "Psychopharmacology"
DOI: 10.1007/s00213-021-05899-4
Abstract: Alzheimer's disease (AD) is a most common neurodegenerative disorder worldwide. Because of its complex pathogenesis, the prevention and therapies of AD still are a severe challenge. Evidence suggested that crocin, the major component of saffron,… read more here.
Keywords: crocin endogenous; n2a app695swe; induced neurotoxicity; app695swe cells ... See more keywords
Mini review–vanadium-induced neurotoxicity and possible targets
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DOI: 10.1007/s10072-019-04188-5
Abstract: Vanadium, a transition metal, ubiquitous in nature is known to have therapeutic effect as well as toxic effect. It is known to possess antidiabetic, antitumor and antiparasitic activity. However, on long term exposure, it produces… read more here.
Keywords: possible targets; induced neurotoxicity; review; neurotoxicity ... See more keywords
Neuroprotective effects of carvacrol against cadmium-induced neurotoxicity in rats: role of oxidative stress, inflammation and apoptosis.
Sign Up to like & getrecommendations! Published in 2022 at "Metabolic brain disease"
DOI: 10.1007/s11011-022-00945-2
Abstract: Cadmium (Cd), is a heavy metal reported to be associated with oxidative stress and inflammation. In this paper, we investigated the possible protective effects of carvacrol against Cd-induced neurotoxicity in rats. Adult male Sprague Dawley… read more here.
Keywords: effects carvacrol; oxidative stress; induced neurotoxicity; neurotoxicity ... See more keywords
Syringin Prevents Aβ25-35-Induced Neurotoxicity in SK-N-SH and SK-N-BE Cells by Modulating miR-124-3p/BID Pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Neurochemical research"
DOI: 10.1007/s11064-021-03240-1
Abstract: Alzheimer's disease (AD) is a neurodegenerative disorder disease, disturbing people's normal life. Syringin was mentioned to antagonize Amyloid-β (Aβ)-induced neurotoxicity. However, the action mechanism is still not fully elucidated. This study aimed to explore a… read more here.
Keywords: induced neurotoxicity; syringin; bid; mir 124 ... See more keywords
Curcumin Attenuates the PERK-eIF2α Signaling to Relieve Acrylamide-Induced Neurotoxicity in SH‑SY5Y Neuroblastoma Cells
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DOI: 10.1007/s11064-021-03504-w
Abstract: Curcumin is a natural polyphenolic compound with neuroprotective and antioxidant properties. Acrylamide (ACR) is a by-product of food processing that produces neurotoxicity in humans and animals. The pancreatic endoplasmic reticulum kinase (PERK)-eukaryotic initiation factor-2α (eIF2α)… read more here.
Keywords: eif2 signaling; sy5y; induced neurotoxicity; acr induced ... See more keywords
Morin protects against acrylamide-induced neurotoxicity in rats: an investigation into different signal pathways
Sign Up to like & getrecommendations! Published in 2021 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-021-14049-4
Abstract: The presented study investigates the effects of morin against toxicity induced by acrylamide (ACR) in the brains of Sprague Dawley rats. In this study, neurotoxicity was induced by orally administering 38.27 mg/kg/b.w ACR to rats… read more here.
Keywords: protects acrylamide; neurotoxicity rats; acrylamide induced; induced neurotoxicity ... See more keywords
Euxanthone Ameliorates Sevoflurane-Induced Neurotoxicity in Neonatal Mice
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DOI: 10.1007/s12031-019-01303-1
Abstract: Sevoflurane is a widely used anesthetic. A series of recent studies have shown that exposure to sevoflurane at an early stage is a risk factor for the development of learning and memory dysfunction. Euxanthone is… read more here.
Keywords: euxanthone; induced neurotoxicity; expression; sevoflurane induced ... See more keywords