Sortilin 1 knockout alters basal adipose glucose metabolism but not diet‐induced obesity in mice
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Letters"
DOI: 10.1002/1873-3468.12610
Abstract: Sortilin 1 (Sort1) is a trafficking receptor that has been implicated in the regulation of plasma cholesterol in humans and mice. Here, we use metabolomics and hyperinsulinemic‐euglycemic clamp approaches to obtain further understanding of the… read more here.
Keywords: glucose metabolism; obesity; diet induced; induced obesity ... See more keywords
Cordyceps militaris Polysaccharides Modulate Gut Microbiota and Improve Metabolic Disorders in Mice with Diet-Induced Obesity.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12409
Abstract: BACKGROUND Cordyceps militaris is an edible and medicinal fungus, and its polysaccharides are one of the main pharmacological components, which could exert immunomodulation, anti-oxidation, anti-inflammation, anti-hypolipidemic, and other functions. But the anti-obesity effect of C.… read more here.
Keywords: gut; gut microbiota; cordyceps militaris; militaris polysaccharides ... See more keywords
Quercetin improves high‐fat diet‐induced obesity by modulating gut microbiota and metabolites in C57BL/6J mice
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7575
Abstract: High‐fat diet‐induced obesity is characterized by low‐grade inflammation, which has been linked to gut microbiota dysbiosis. We hypothesized that quercetin supplementation would alter gut microbiota and reduce inflammation in obese mice. Male C57BL/6J mice, 4 weeks… read more here.
Keywords: microbiota; gut microbiota; high fat; induced obesity ... See more keywords
Withaferin A Protects Against High-Fat Diet–Induced Obesity Via Attenuation of Oxidative Stress, Inflammation, and Insulin Resistance
Sign Up to like & getrecommendations! Published in 2018 at "Applied Biochemistry and Biotechnology"
DOI: 10.1007/s12010-018-2920-2
Abstract: Withaferin A (WA), a bioactive constituent derived from Withania somnifera plant, has been shown to exhibit many qualifying properties in attenuating several metabolic diseases. The current investigation sought to elucidate the protective mechanisms of WA… read more here.
Keywords: fat diet; insulin; high fat; induced obesity ... See more keywords
Downregulation of leptin receptor and kisspeptin/GPR54 in the murine hypothalamus contributes to male hypogonadism caused by high-fat diet-induced obesity
Sign Up to like & getrecommendations! Published in 2018 at "Endocrine"
DOI: 10.1007/s12020-018-1646-9
Abstract: PurposeObesity may lead to male hypogonadism, the underlying mechanism of which remains unclear. In the present study, we established a murine model of male hypogonadism caused by high-fat diet-induced obesity to verify the following hypotheses:… read more here.
Keywords: diet induced; male hypogonadism; induced obesity;
Omega-3 Fatty Acids Attenuate Brain Alterations in High-Fat Diet-Induced Obesity Model
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Neurobiology"
DOI: 10.1007/s12035-018-1097-6
Abstract: This study evaluated the effects of omega-3 on inflammation, oxidative stress, and energy metabolism parameters in the brain of mice subjected to high-fat diet-induced obesity model. Body weight and visceral fat weight were evaluated as… read more here.
Keywords: fat diet; diet induced; high fat; induced obesity ... See more keywords
The human symbiont Bacteroides thetaiotaomicron promotes diet-induced obesity by regulating host lipid metabolism
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Microbiology"
DOI: 10.1007/s12275-022-1614-1
Abstract: The gut microbiome plays an important role in lipid metabolism. Consumption of a high-fat diet (HFD) alters the bacterial communities in the gut, leading to metabolic disorders. Several bacterial species have been associated with diet-induced… read more here.
Keywords: induced obesity; expression; lipid metabolism; human symbiont ... See more keywords
Downregulation of HIF complex in the hypothalamus exacerbates diet-induced obesity
Sign Up to like & getrecommendations! Published in 2018 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2018.06.020
Abstract: Hypothalamic hypoxia-inducible factor-1 (HIF-1) can regulate whole-body energy homeostasis in response to changes in blood glucose, suggesting that it acts as a sensor for systemic energy stores. Here, we hypothesized that hypothalamic HIF-1 could be… read more here.
Keywords: hif; hypothalamus; diet induced; induced obesity ... See more keywords
Gut microbial metabolite TMAO contributes to renal dysfunction in a mouse model of diet-induced obesity.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.09.108
Abstract: Emerging evidence shows that obesity induces renal injury and is an independent risk factor for the development of chronic kidney disease (CKD), even without diabetes or hyperglycemia. Although multiple metabolic factors have been suggested to… read more here.
Keywords: obesity; dysfunction; tmao; contributes renal ... See more keywords
Protective and ameliorating effects of probiotics against diet-induced obesity: A review.
Sign Up to like & getrecommendations! Published in 2021 at "Food research international"
DOI: 10.1016/j.foodres.2021.110490
Abstract: Diet-induced obesity is one of the major public health concerns all over the world, and obesity also contributes to the development of other chronic diseases such as non-alcoholic fatty acid liver disease, type 2 diabetes… read more here.
Keywords: induced obesity; effects probiotics; obesity; chronic diseases ... See more keywords
Diet-Induced Obesity HFpEF Murine Models
Sign Up to like & getrecommendations! Published in 2018 at "JACC: Basic to Translational Science"
DOI: 10.1016/j.jacbts.2018.01.004
Abstract: We read with great interest the state-of-the-art review from Valero-Munoz et al. [(1)][1] in a recent issue of JACC: Basic to Translational Science . The authors described the more commonly used murine models of heart failure… read more here.
Keywords: murine models; murine; diet induced; obesity hfpef ... See more keywords