Tumor‐Induced Osteomalacia: Treatment Progress Using Burosumab, an Anti‐FGF23 Monoclonal Antibody
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4280
Abstract: I n this issue of JBMR, Jan de Beur and colleagues (1) report the primary analysis and findings up to closure of their prospective, open-label, single-arm, phase 2 study (NCT02304367) to evaluate the safety and… read more here.
Keywords: treatment; tumor induced; tio; induced osteomalacia ... See more keywords
Clinical Challenges in Diagnosis, Tumor Localization and Treatment of Tumor‐Induced Osteomalacia: Outcome of a Retrospective Surveillance
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DOI: 10.1002/jbmr.4620
Abstract: Tumor‐induced osteomalacia (TIO) is an acquired fibroblast growth factor 23 (FGF23)‐related hypophosphatemic osteomalacia caused by phosphaturic mesenchymal tumors (PMTs) developed in the bone or soft tissue. Diagnostic delay should be addressed, and ideal techniques to… read more here.
Keywords: tumor induced; tomography; induced osteomalacia; treatment ... See more keywords
Tumor-induced osteomalacia in association with PTEN-negative Cowden syndrome
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DOI: 10.1007/s00198-017-4372-x
Abstract: Tumor-induced osteomalacia (TIO) is a rare paraneoplastic condition in which phosphaturic mesenchymal tumors (PMTs) secrete high levels of fibroblast growth factor 23 (FGF23) into the circulation. This results in renal phosphate wasting, hypophosphatemia, muscle weakness,… read more here.
Keywords: cowden syndrome; tumor induced; tio; induced osteomalacia ... See more keywords
Tumor-Induced Osteomalacia
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DOI: 10.1007/s00223-020-00691-6
Abstract: Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by tumoral production of fibroblast growth factor 23 (FGF23). The hallmark biochemical features include hypophosphatemia due to renal phosphate wasting, inappropriately normal or frankly low 1,25-dihydroxy-vitamin… read more here.
Keywords: fgf23; tumor induced; tio; induced osteomalacia ... See more keywords
Epidemiology of Tumor-Induced Osteomalacia in Denmark
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DOI: 10.1007/s00223-021-00843-2
Abstract: Tumor-induced osteomalacia (TIO) is a rare, acquired condition of phosphate wasting due to phosphaturic mesenchymal tumors. Because the incidence and prevalence of TIO is unknown, we conducted an observational cohort study using national Danish health… read more here.
Keywords: per 100; 100 000; tumor induced; tio ... See more keywords
Ameloblastic Fibroodontoma of Mandible Causing Tumor Induced Osteomalacia: A Case Report with Review of 88 Phosphaturic Oral Neoplasms
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DOI: 10.1007/s12105-020-01267-4
Abstract: Tumor induced osteomalacia (TIO) is a rare paraneoplastic syndrome associated with tumors secreting fibroblast growth factor 23, which induces osteomalacia. Microscopically, these tumors most commonly show benign phosphaturic mesenchymal tumors. We report the first case… read more here.
Keywords: case; tumor induced; oral neoplasms; induced osteomalacia ... See more keywords
Extended Whole-body Ga-68 DOTATATE PET-CT in evaluating Tumour-Induced Osteomalacia: Case report and review of literature
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DOI: 10.1007/s13139-021-00695-6
Abstract: Tumour-induced osteomalacia is a rare paraneoplastic syndrome that manifests as chronic hypophosphataemia, non-specific bone pain and muscle weakness. It is generally caused by phosphaturic mesenchymal tumour (PMT), which is uncommonly associated with synchronous tumours. However,… read more here.
Keywords: extended whole; dotatate pet; disease; induced osteomalacia ... See more keywords
Breast Carcinoma Shown on 99mTc-HYNIC-TOC Study Performed to Evaluate Tumor-Induced Osteomalacia.
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DOI: 10.1097/rlu.0000000000003861
Abstract: ABSTRACT A 74-year-old woman with a history of suspected tumor-induced osteomalacia underwent 99mTc-HYNIC-TOC scintigraphy to search potential culprit tumor. The images showed one in the middle shaft of left femur without corresponding morphology change on… read more here.
Keywords: 99mtc hynic; hynic toc; tumor induced; induced osteomalacia ... See more keywords
Successful treatment of tumour-induced osteomalacia after resection of an oral peripheral ossifying fibroma
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DOI: 10.1136/bcr-2016-218637
Abstract: Tumour-induced osteomalacia is a paraneoplastic syndrome wherein bone is affected by a hormone from a tumour that causes renal phosphate wasting and hypophosphataemia. Here, we present the case of a 31-year-old man who has been… read more here.
Keywords: treatment tumour; successful treatment; osteomalacia resection; induced osteomalacia ... See more keywords
Challenging case of tumour-induced osteomalacia
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DOI: 10.1136/bcr-2022-249200
Abstract: Tumour-induced osteomalacia (TIO), also known as oncogenic osteomalacia, is an uncommon paraneoplastic syndrome which poses a diagnostic challenge. The hallmark feature is severe acquired hypophosphataemic osteomalacia due to renal phosphate wasting because of increased secretion… read more here.
Keywords: case tumour; tumour induced; induced osteomalacia; challenging case ... See more keywords
Tumour-induced osteomalacia due to residual benign glomangioma
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DOI: 10.1136/bcr-2022-250237
Abstract: Tumour-induced osteomalacia (TIO) is a rare paraneoplastic syndrome. The constellation of findings of unprovoked fractures, hypophosphataemia, urinary phosphate wasting and a negative genetic evaluation suggest a TIO diagnosis. Tumours leading to TIO are often small… read more here.
Keywords: due residual; induced osteomalacia; osteomalacia due; tumour induced ... See more keywords