Mitochondrial Stress Induced p53 Attenuates HIF-1α Activity by Physical Association and Enhanced Ubiquitination
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DOI: 10.1038/onc.2016.211
Abstract: Retrograde signaling is a mechanism by which mitochondrial dysfunction is communicated to the nucleus for inducing a metabolic shift essential for cell survival. Previously, we showed that partial mitochondrial DNA (mtDNA) depletion in different cell… read more here.
Keywords: hif; mitochondrial stress; stress induced; stress ... See more keywords