Octreotide alleviates pancreatic damage caused by paraquat in rats by reducing inflammatory responses and oxidative stress.
Sign Up to like & getrecommendations! Published in 2020 at "Environmental toxicology and pharmacology"
DOI: 10.1016/j.etap.2020.103456
Abstract: This study explores the efficacy and mechanism by which octreotide (OCT) alleviates paraquat (PQ)-induced pancreatic injury. Twenty-four adult male rats were randomly divided into three groups: the normal control (NC), PQ poisoning, and OCT treatment… read more here.
Keywords: induced pancreatic; pancreatic damage; group; oxidative stress ... See more keywords
IKBKE Is Required during KRAS-Induced Pancreatic Tumorigenesis.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer research"
DOI: 10.1158/0008-5472.can-15-1684
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies lacking effective therapeutic strategies. Here, we show that the noncanonical IκB-related kinase, IKBKE, is a critical oncogenic effector during KRAS-induced pancreatic transformation. Loss of IKBKE… read more here.
Keywords: kras induced; ikbke required; pancreatic tumorigenesis; induced pancreatic ... See more keywords
Ameliorative Effects of Flavonoids from Platycodon grandiflorus Aerial Parts on Alloxan-Induced Pancreatic Islet Damage in Zebrafish
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DOI: 10.3390/nu15071798
Abstract: Platycodon grandiflorus (balloon flower), used as a food reserve as well as in traditional herbal medicine, is known for its multiple beneficial effects. In particular, this plant is widely used as a vegetable in Republic… read more here.
Keywords: platycodon grandiflorus; ameliorative effects; induced pancreatic; pancreatic islet ... See more keywords
Sheng-jiang powder ameliorates obesity-induced pancreatic inflammatory injury via stimulating activation of the AMPK signalling pathway in rats
Sign Up to like & getrecommendations! Published in 2018 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v24.i39.4448
Abstract: AIM To investigate the mechanisms by which Sheng-jiang powder (SJP) ameliorates obesity-induced pancreatic inflammatory injury. METHODS Sprague-Dawley rats were randomized into three groups: normal group (NG), obese group (HLG), or SJP treatment group (HSG). Obesity… read more here.
Keywords: induced pancreatic; pancreatic inflammatory; obesity induced; inflammatory injury ... See more keywords
CBX3 Regulated By YBX1 Promotes Smoking-induced Pancreatic Cancer Progression via Inhibiting SMURF2 Expression
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.68995
Abstract: As a key reversible and heritable mechanism of transcriptional regulation, the epigenetic modification plays a crucial role in tumorigenesis. Of note, tobacco smoking induces epigenetic modifications to promote pancreatic cancer development. Chromobox protein homolog 3… read more here.
Keywords: pancreatic cancer; induced pancreatic; cbx3; cancer progression ... See more keywords