Microstructural white matter alterations in patients with drug induced parkinsonism
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DOI: 10.1002/hbm.23809
Abstract: Drug‐induced parkinsonism (DIP) is the second most common etiology of parkinsonism. And yet, there is little information on structural imaging in DIP to elucidate the accurate underlying pathomechanisms. To investigate microstructural white matter (WM) in… read more here.
Keywords: drug induced; dip; parkinsonism; microstructural white ... See more keywords
Aripiprazole-induced Parkinsonism with pregabalin as a confounder
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DOI: 10.1007/s13760-020-01370-x
Abstract: Aripiprazole is an atypical anti-psychotic with partial agonism at D2, 5-HT1a, and inverse agonism at 5-HT2a, 5-HT2c [1] Being a partial D2-agonist, it is theoretically less likely to cause extrapyramidal effects. In its initial years,… read more here.
Keywords: aripiprazole induced; case; parkinsonism; anti psychotic ... See more keywords
Dexmedetomidine attenuates the induction and reverses the progress of 6-hydroxydopamine- induced parkinsonism; involvement of KATP channels, alpha 2 adrenoceptors and anti-inflammatory mechanisms.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2019.114743
Abstract: BACKGROUND Studies have shown that dexmedetomidine (DEX), a potent α2-adrenoceptors agonist provides neuroprotection through suppression of inflammatory response. In present study, we examined effect of DEX and its underlying mechanisms on the induction and progress… read more here.
Keywords: katp channels; induced parkinsonism; ohda induced; dex ... See more keywords
Shared functional neural substrates in Parkinson's disease and drug-induced parkinsonism: association with dopaminergic depletion
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DOI: 10.1038/s41598-020-68514-0
Abstract: While drug-induced parkinsonism (DIP) is mainly caused by blockage of the dopaminergic pathway, multiple neurotransmitter systems besides the dopaminergic system are involved in Parkinson’s disease (PD). Therefore, alterations found in both DIP and PD might… read more here.
Keywords: parkinson disease; induced parkinsonism; cortex; drug induced ... See more keywords
Approaching drug-induced parkinsonism from a neurohospitalist perspective
Sign Up to like & getrecommendations! Published in 2019 at "Expert Review of Neurotherapeutics"
DOI: 10.1080/14737175.2019.1569515
Abstract: In the hospital setting, a neurologist may be asked to help differentiate drug-induced parkinsonism from idiopathic Parkinson’s disease. While ancillary tests can be confirmatory, a proper history ... read more here.
Keywords: approaching drug; parkinsonism neurohospitalist; induced parkinsonism; drug induced ... See more keywords
Tramadol-induced parkinsonism: a case report of a 75-year-old woman
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Basic and Clinical Physiology and Pharmacology"
DOI: 10.1515/jbcpp-2018-0113
Abstract: Abstract Adverse drug reaction (ADR) is a form of unwanted reaction and is the crucial reason for illness and death. Tramadol-induced parkinsonism is a kind of ADR that occurs after the repeated intake of tramadol.… read more here.
Keywords: tramadol; tramadol induced; parkinsonism; induced parkinsonism ... See more keywords
Updated Perspectives on the Management of Drug-Induced Parkinsonism (DIP): Insights from the Clinic
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DOI: 10.2147/tcrm.s360268
Abstract: Abstract Parkinsonism refers to the clinical combination of bradykinesia, rigidity, tremor, and postural instability. Parkinsonism is often neurodegenerative, but it can be secondary or iatrogenic, as in drug-induced parkinsonism (DIP), which is the topic of… read more here.
Keywords: drug induced; parkinsonism dip; parkinsonism; management ... See more keywords
Trends in the Prevalence of Drug-Induced Parkinsonism in Korea
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DOI: 10.3349/ymj.2019.60.8.760
Abstract: Purpose Discontinuation of offending drugs can prevent drug-induced parkinsonism (DIP) before it occurs and reverse or cure it afterwards. The aim of this study was to investigate the prevalence of DIP and the utilization of… read more here.
Keywords: offending drugs; induced parkinsonism; drug induced; dip ... See more keywords
Pathophysiological Mechanisms of Antipsychotic-Induced Parkinsonism
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DOI: 10.3390/biomedicines10082010
Abstract: Among neurological adverse reactions in patients with schizophrenia treated with antipsychotics (APs), drug-induced parkinsonism (DIP) is the most common motility disorder caused by drugs affecting dopamine receptors. One of the causes of DIP is the… read more here.
Keywords: antipsychotic induced; mechanisms antipsychotic; parkinsonism; pathophysiological mechanisms ... See more keywords