Stimulation of AMPK Prevents Diabetes-Induced Photoreceptor Cell Degeneration
Sign Up to like & getrecommendations! Published in 2021 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2021/5587340
Abstract: Diabetic retinopathy (DR) is a kind of severe retinal neurodegeneration. The advanced glycation end products (AGEs) affect autophagy, and mitochondrial function is involved in DR. Adenosine-activated protein kinase (AMPK) is an important metabolic sensor that… read more here.
Keywords: induced photoreceptor; degeneration; ampk; expression ... See more keywords
Cellular-scale evaluation of induced photoreceptor degeneration in the living primate eye.
Sign Up to like & getrecommendations! Published in 2019 at "Biomedical optics express"
DOI: 10.1364/boe.10.000066
Abstract: Progress is needed in developing animal models of photoreceptor degeneration and evaluating such models with longitudinal, noninvasive techniques. We employ confocal scanning laser ophthalmoscopy, optical coherence tomography (OCT) and high-resolution retinal imaging to noninvasively observe… read more here.
Keywords: photoreceptor degeneration; induced photoreceptor; cellular scale; degeneration ... See more keywords