IFN‐γ stimulates CpG‐induced IL‐10 production in B cells via p38 and JNK signalling pathways
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Immunology"
DOI: 10.1002/eji.201847578
Abstract: The production of IL‐10, a potent immunosuppressive cytokine, must be strictly regulated to ensure a balanced immune response. IFN‐γ, a key cytokine in multiple immune processes and pathologies, is known as an inhibitor of IL‐10… read more here.
Keywords: p38 jnk; production; induced production; ifn ... See more keywords
Inflammatory signal induced IL-10 production of marginal zone B-cells depends on CREB.
Sign Up to like & getrecommendations! Published in 2019 at "Immunology letters"
DOI: 10.1016/j.imlet.2019.06.004
Abstract: IL-10 is a suppressive cytokine that has been implicated in the pathophysiology of autoimmune disorders and can be produced by different cell types such as regulatory B-cells. Our previous work showed that under inflammatory condition… read more here.
Keywords: inflammatory signal; production; induced production; signal induced ... See more keywords
Toll-like receptors in the mechanism of tributyltin-induced production of pro-inflammatory cytokines, IL-1β and IL-6.
Sign Up to like & getrecommendations! Published in 2022 at "Toxicology"
DOI: 10.1016/j.tox.2022.153177
Abstract: Tributyltin (TBT) is an environmental contaminant due to its use in a variety of applications as a biocide, including in marine anti-fouling paints. It has been detected in a number of human tissues including blood.… read more here.
Keywords: inflammatory cytokines; pro inflammatory; toll like; induced production ... See more keywords
Investigating the immunomodulatory activities of omadacycline
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkac356
Abstract: Abstract Background Apart from their antimicrobial activities, some antibiotics have immunomodulatory effects on host cells, particularly monocytes. Because hyperactivation of the pro-inflammatory cytokine response contributes to acute lung injury in patients with bacterial pneumonia and… read more here.
Keywords: immunomodulatory activities; activities omadacycline; induced production; lps induced ... See more keywords
HIV and HIV‐Tat inhibit LPS‐induced IL‐27 production in human macrophages by distinct intracellular signaling pathways
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Leukocyte Biology"
DOI: 10.1189/jlb.4a0716-332rr
Abstract: Monocyte‐derived Mϕs (MDMs) from HIV‐infected patients and MDM infected in vitro with HIV exhibit a reduced ability to secrete various cytokines, including IL‐12. Recently, IL‐27, an IL‐12 family cytokine, was shown to inhibit HIV replication… read more here.
Keywords: lps induced; production; induced production; hiv ... See more keywords