TRPA1 channel participates in tacrolimus-induced pruritus in a chronic contact hypersensitivity murine model.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of dermatological science"
DOI: 10.1016/j.jdermsci.2017.10.012
Abstract: Tacrolimus ointment (FK506), a calcineurin inhibitor, is a widely used topical medication in atopic dermatitis (AD) [1]. Although it is effective, pruritus and stinging sensation are common, particularly in AD patients [1]. Mediators of mast… read more here.
Keywords: pruritus; model; tacrolimus induced; hypersensitivity ... See more keywords
Prevention and Treatment of Neuraxial Morphine-Induced Pruritus: A Scoping Review
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DOI: 10.2147/jpr.s361225
Abstract: Abstract The addition of morphine to neuraxial anaesthesia leads to improved postoperative analgesia and lower opioid consumption, but is often accompanied by pruritus. Studies on preventing or treating pruritus show contradictory results. Our objective was… read more here.
Keywords: morphine induced; induced pruritus; neuraxial morphine; morphine ... See more keywords
Berbamine Reduces Chloroquine-Induced Itch in Mice through Inhibition of MrgprX1
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DOI: 10.3390/ijms232214321
Abstract: Chloroquine (CQ) is an antimalaria drug that has been widely used for decades. However, CQ-induced pruritus remains one of the major obstacles in CQ treatment for uncomplicated malaria. Recent studies have revealed that MrgprX1 plays… read more here.
Keywords: induced pruritus; induced itch; mrgprx1; berbamine ... See more keywords