Galangin ameliorates Imiquimod-Induced psoriasis-like skin inflammation in BALB/c mice via down regulating NF-κB and activation of Nrf2 signaling pathways.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.107754
Abstract: Psoriasis is a most common chronic autoimmune-arbitrated cutaneous inflammatory skin disorder by unclear pathogenesis. In this current study we demonstrated the effect of galangin (GAL) on imiquimod (IMQ)-induced psoriasis-like skin inflammation and decipher its possible… read more here.
Keywords: induced psoriasis; skin inflammation; psoriasis; like skin ... See more keywords
Histological Comparison of TNF-α Inhibitor-Induced Psoriasis and Psoriasis Vulgaris.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2020.01.006
Abstract: BACKGROUND Tumor necrosis factor-α inhibitor-induced psoriasis (TNFI-psoriasis) is a paradoxical reaction characterized by development of a psoriasiform rash that mimics idiopathic psoriasis subtypes both clinically and histologically. Few studies have investigated histologic features of TNFI-induced… read more here.
Keywords: inhibitor induced; induced psoriasis; tnfi psoriasis; idiopathic psoriasis ... See more keywords
Chrysin alleviates imiquimod-induced psoriasis-like skin inflammation and reduces the release of CCL20 and antimicrobial peptides
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-60050-1
Abstract: Psoriasis is a common non-contagious chronic inflammatory skin lesion, with frequent recurrence. It mainly occurs due to aberrant regulation of the immune system leading to abnormal proliferation of skin cells. However, the pathogenic mechanisms of… read more here.
Keywords: induced psoriasis; chrysin; psoriasis; like skin ... See more keywords
Phosphatidylserine Topically Attenuates Imiquimod-induced Psoriasis Through Inflammation Inhibition in Mice
Sign Up to like & getrecommendations! Published in 2024 at "Drug Research"
DOI: 10.1055/a-2419-9616
Abstract: Abstract Background Psoriasis is a chronic skin condition that is associated with persistent inflammation and skin lesions. Topical therapy has been a promising approach to the alleviation of psoriasis through the application of anti-inflammatory agents.… read more here.
Keywords: induced psoriasis; imq induced; inhibition; pasi score ... See more keywords
Asiatic acid exerts an anti-psoriatic effect in the imiquimod-induced psoriasis model in mice
Sign Up to like & getrecommendations! Published in 2022 at "Immunopharmacology and Immunotoxicology"
DOI: 10.1080/08923973.2022.2048849
Abstract: Abstract Background: Psoriasis is a common skin disorder related to inflammation and immune response. However, many treatment modalities are present in the clinics, and drug conformity halts chronic treatment. Therefore, novel treatment options are still… read more here.
Keywords: imiquimod induced; acid; asiatic acid; induced psoriasis ... See more keywords
Birinapant improves imiquimod-induced psoriasis in BALB/c mice
Sign Up to like & getrecommendations! Published in 2025 at "Immunopharmacology and Immunotoxicology"
DOI: 10.1080/08923973.2025.2470345
Abstract: Abstract Objectives This study investigates the effects of birinapant, a novel compound, on psoriasis-like symptoms induced by imiquimod in Balb/c mice. Material and methods Male Balb/c mice were treated with imiquimod (IMQ) to induce psoriasis-like… read more here.
Keywords: induced psoriasis; balb mice; psoriasis; birinapant ... See more keywords
Integrated Metabolomics and Transcriptomics Analyses Reveal Histidine Metabolism Plays an Important Role in Imiquimod-Induced Psoriasis-like Skin Inflammation.
Sign Up to like & getrecommendations! Published in 2021 at "DNA and cell biology"
DOI: 10.1089/dna.2021.0465
Abstract: Psoriasis is a chronic inflammatory skin disease characterized by massive keratinocyte proliferation and immune cell infiltration into the epidermis. However, the specific mechanisms underlying the development of psoriasis remain unclear. Untargeted metabolomics and transcriptomics have… read more here.
Keywords: induced psoriasis; metabolism; metabolomics transcriptomics; psoriasis ... See more keywords
Two Cases of Drug-Induced Psoriasis from Second Generation Androgen Receptor Blockers.
Sign Up to like & getrecommendations! Published in 2024 at "Clinical and experimental dermatology"
DOI: 10.1093/ced/llae509
Abstract: This is two cases of Androgen-Receptor Induced Psoriasis. Both cases ultimately continued the medications due to risk/benefit analysis by multidisciplinary teams. Both cases also improved with topical ultrapotent steroids. This is the first case series… read more here.
Keywords: receptor; induced psoriasis; drug; two cases ... See more keywords
Widespread imiquimod-induced psoriasis like eruption: case report and analysis of mast cell infiltration.
Sign Up to like & getrecommendations! Published in 2024 at "Clinical and experimental dermatology"
DOI: 10.1093/ced/llae527
Abstract: We report a case of psoriasis-like eruptions after topical imiquimod. We demonstrated that MCs are significantly associated with imiquimod-induced psoriasis and supports previous reports. Based on the differences in mast cell counts, it can be… read more here.
Keywords: psoriasis like; imiquimod induced; induced psoriasis; mast cell ... See more keywords
Local production of prolactin in lesions may play a pathogenic role in psoriatic patients and imiquimod‐induced psoriasis‐like mouse model
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Dermatology"
DOI: 10.1111/exd.13772
Abstract: Human prolactin (PRL) is a well‐known hormone for pituitary of lactation and reproduction, but it also has immunostimulatory effect in some inflammatory or autoimmune diseases including psoriasis, which has not been well elucidated. This study… read more here.
Keywords: induced psoriasis; group; psoriasis; prl ... See more keywords
P69: BIOLOGIC THERAPY‐INDUCED PSORIASIS: AN ILLUSTRATIVE CASE
Sign Up to like & getrecommendations! Published in 2018 at "Internal Medicine Journal"
DOI: 10.1111/imj.69_14077
Abstract: Introduction Psoriasis is a T‐cell driven, chronic inflammatory skin disease. In recent literature, biologics and small molecule therapies have been reported to induce psoriasis de novo, including tumour necrosis factor inhibitors, rituximab, abatacept and anti‐programmed… read more here.
Keywords: rituximab; induced psoriasis; initiation; case ... See more keywords