Galangin ameliorates Imiquimod-Induced psoriasis-like skin inflammation in BALB/c mice via down regulating NF-κB and activation of Nrf2 signaling pathways.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.107754
Abstract: Psoriasis is a most common chronic autoimmune-arbitrated cutaneous inflammatory skin disorder by unclear pathogenesis. In this current study we demonstrated the effect of galangin (GAL) on imiquimod (IMQ)-induced psoriasis-like skin inflammation and decipher its possible… read more here.
Keywords: induced psoriasis; skin inflammation; psoriasis; like skin ... See more keywords
Histological Comparison of TNF-α Inhibitor-Induced Psoriasis and Psoriasis Vulgaris.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2020.01.006
Abstract: BACKGROUND Tumor necrosis factor-α inhibitor-induced psoriasis (TNFI-psoriasis) is a paradoxical reaction characterized by development of a psoriasiform rash that mimics idiopathic psoriasis subtypes both clinically and histologically. Few studies have investigated histologic features of TNFI-induced… read more here.
Keywords: inhibitor induced; induced psoriasis; tnfi psoriasis; idiopathic psoriasis ... See more keywords
Chrysin alleviates imiquimod-induced psoriasis-like skin inflammation and reduces the release of CCL20 and antimicrobial peptides
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-60050-1
Abstract: Psoriasis is a common non-contagious chronic inflammatory skin lesion, with frequent recurrence. It mainly occurs due to aberrant regulation of the immune system leading to abnormal proliferation of skin cells. However, the pathogenic mechanisms of… read more here.
Keywords: induced psoriasis; chrysin; psoriasis; like skin ... See more keywords
Asiatic acid exerts an anti-psoriatic effect in the imiquimod-induced psoriasis model in mice
Sign Up to like & getrecommendations! Published in 2022 at "Immunopharmacology and Immunotoxicology"
DOI: 10.1080/08923973.2022.2048849
Abstract: Abstract Background: Psoriasis is a common skin disorder related to inflammation and immune response. However, many treatment modalities are present in the clinics, and drug conformity halts chronic treatment. Therefore, novel treatment options are still… read more here.
Keywords: imiquimod induced; acid; asiatic acid; induced psoriasis ... See more keywords
Integrated Metabolomics and Transcriptomics Analyses Reveal Histidine Metabolism Plays an Important Role in Imiquimod-Induced Psoriasis-like Skin Inflammation.
Sign Up to like & getrecommendations! Published in 2021 at "DNA and cell biology"
DOI: 10.1089/dna.2021.0465
Abstract: Psoriasis is a chronic inflammatory skin disease characterized by massive keratinocyte proliferation and immune cell infiltration into the epidermis. However, the specific mechanisms underlying the development of psoriasis remain unclear. Untargeted metabolomics and transcriptomics have… read more here.
Keywords: induced psoriasis; metabolism; metabolomics transcriptomics; psoriasis ... See more keywords
Local production of prolactin in lesions may play a pathogenic role in psoriatic patients and imiquimod‐induced psoriasis‐like mouse model
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Dermatology"
DOI: 10.1111/exd.13772
Abstract: Human prolactin (PRL) is a well‐known hormone for pituitary of lactation and reproduction, but it also has immunostimulatory effect in some inflammatory or autoimmune diseases including psoriasis, which has not been well elucidated. This study… read more here.
Keywords: induced psoriasis; group; psoriasis; prl ... See more keywords
P69: BIOLOGIC THERAPY‐INDUCED PSORIASIS: AN ILLUSTRATIVE CASE
Sign Up to like & getrecommendations! Published in 2018 at "Internal Medicine Journal"
DOI: 10.1111/imj.69_14077
Abstract: Introduction Psoriasis is a T‐cell driven, chronic inflammatory skin disease. In recent literature, biologics and small molecule therapies have been reported to induce psoriasis de novo, including tumour necrosis factor inhibitors, rituximab, abatacept and anti‐programmed… read more here.
Keywords: rituximab; induced psoriasis; initiation; case ... See more keywords
Topical astilbin ameliorates imiquimod‐induced psoriasis‐like skin lesions in SKH‐1 mice via suppression dendritic cell‐Th17 inflammation axis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17184
Abstract: Astilbin, an essential component of Rhizoma smilacis glabrae, exerts significant antioxidant and anti‐inflammatory effects against various autoimmune diseases. We have previously reported that astilbin decreases proliferation and improves differentiation of HaCaT keratinocytes in a psoriatic… read more here.
Keywords: psoriasis like; induced psoriasis; like skin; differentiation ... See more keywords
P093/O16 IL-36 signaling in keratinocytes is mandatory in imiquimod-induced psoriasis in mice
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-ewrr2019.82
Abstract: Career situation of first and presenting author Post-doctoral fellow. Introduction A large body of evidence indicates that IL-36R signaling plays an important role in the pathogenesis of psoriasis. For instance, IL-36 receptor (IL-36R)-deficient mice showed… read more here.
Keywords: 36r mice; mice; psoriasis; signaling keratinocytes ... See more keywords
KdPT alleviates imiquimod-induced psoriasis-like skin lesion in mice via inhibiting proliferation and inflammation response.
Sign Up to like & getrecommendations! Published in 2022 at "Die Pharmazie"
DOI: 10.1691/ph.2022.1970
Abstract: Psoriasis is a complex chronic skin inflammatory disease characterized by abnormal proliferation, differentiation of keratinocytes and infiltration of lymphocytes and neutrophils. The tripeptide KdPT, structurally derived from the C-terminal amino acid of alpha-melanocyte-stimulating hormone, has… read more here.
Keywords: proliferation; inhibiting proliferation; induced psoriasis; psoriasis ... See more keywords
Probiotic Lactobacillus sakei proBio-65 Extract Ameliorates the Severity of Imiquimod Induced Psoriasis-Like Skin Inflammation in a Mouse Model
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2018.01021
Abstract: This study was designed to evaluate the protective effect of ethanol extract (SEL001) isolated from a potent probiotic strain Lactobacillus sakei proBio-65 on imiquimod (IMQ)-induced psoriasis-like skin inflammation in a mouse model. Histopathological and histomorphometrical… read more here.
Keywords: treated groups; induced psoriasis; imq; lactobacillus sakei ... See more keywords