Chlorogenic acid protective effects on paraquat-induced pulmonary oxidative damage and fibrosis in rats.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.23352
Abstract: Paraquat (PQ) is a widely used herbicide that can cause severe oxidative and fibrotic injuries in lung tissue. Due to the antioxidant and anti-inflammatory properties of chlorogenic acid (CGA), the present study investigated its effects… read more here.
Keywords: lung tissue; acid protective; cga; chlorogenic acid ... See more keywords
Grading Bleomycin‐Induced Pulmonary Fibrosis in ex vivo Mouse Lungs Using Ultrasound Image Analysis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Ultrasound in Medicine"
DOI: 10.1002/jum.15448
Abstract: The aim of this study was to assess bleomycin‐induced pulmonary fibrosis on ex vivo mouse lungs using ultrasound image grading and texture analysis. read more here.
Keywords: bleomycin induced; fibrosis vivo; mouse lungs; induced pulmonary ... See more keywords
Vitamin D protects against particles‐caused lung injury through induction of autophagy in an Nrf2‐dependent manner
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Toxicology"
DOI: 10.1002/tox.22726
Abstract: Fine particulate matter is a well‐known air pollutant threatening public health. Studies have confirmed long‐term exposure to the particles could decrease the pulmonary function, induce asthma exacerbation, and chronic obstructive pulmonary disease, as well as… read more here.
Keywords: nrf2 dependent; autophagy nrf2; induced pulmonary; induction autophagy ... See more keywords
Pachymic acid ameliorates bleomycin-induced pulmonary fibrosis through inhibiting endoplasmic reticulum stress in rats.
Sign Up to like & getrecommendations! Published in 2023 at "Environmental toxicology"
DOI: 10.1002/tox.23824
Abstract: The effect of pachymic acid (PA) on pulmonary fibrosis in rats was expected to be investigated in this study. Firstly, bleomycin (BLM) was used to establish pulmonary fibrosis rat model, then PA (10, 20, or… read more here.
Keywords: lung tissue; blm; pulmonary fibrosis; induced pulmonary ... See more keywords
Ibrutinib Exacerbates Bleomycin-Induced Pulmonary Fibrosis via Promoting Inflammation
Sign Up to like & getrecommendations! Published in 2018 at "Inflammation"
DOI: 10.1007/s10753-018-0745-3
Abstract: Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible lung disease with high mortality rate. The etiology is unknown and treatment choices are limited. Thus, there is great interest to investigate novel agents for IPF… read more here.
Keywords: bleomycin induced; ibrutinib; fibrosis; induced pulmonary ... See more keywords
Interleukin-37 Attenuates Bleomycin-Induced Pulmonary Inflammation and Fibrosis in Mice
Sign Up to like & getrecommendations! Published in 2018 at "Inflammation"
DOI: 10.1007/s10753-018-0820-9
Abstract: Pulmonary fibrosis is a disease with chronic inflammation and excessive collagen deposition for which there is no effective treatments. Interleukin (IL)-37 is a newly identified anti-inflammatory cytokine but its role in pulmonary fibrosis remains unclear.… read more here.
Keywords: bleomycin induced; fibrosis; induced pulmonary; fibrosis mice ... See more keywords
p38 Inhibition Ameliorates Inspiratory Resistive Breathing-Induced Pulmonary Inflammation
Sign Up to like & getrecommendations! Published in 2018 at "Inflammation"
DOI: 10.1007/s10753-018-0831-6
Abstract: Inspiratory resistive breathing (IRB), a hallmark of obstructive airway diseases, is associated with strenuous contractions of the inspiratory muscles and increased negative intrathoracic pressures that act as an injurious stimulus to the lung. We have… read more here.
Keywords: pulmonary inflammation; inspiratory resistive; induced pulmonary; inflammation ... See more keywords
Metabolomic study on bleomycin and polyhexamethylene guanidine phosphate-induced pulmonary fibrosis mice models
Sign Up to like & getrecommendations! Published in 2019 at "Metabolomics"
DOI: 10.1007/s11306-019-1574-6
Abstract: Polyhexamethylene guanidine phosphate (PHMG) has been used as a disinfectant and biocide, and was known to be harmless and non-toxic. However, in 2011, PHMG used as a humidifier disinfectant was reported to be associated with… read more here.
Keywords: guanidine phosphate; fibrosis; induced pulmonary; polyhexamethylene guanidine ... See more keywords
Genetic knockout and pharmacologic inhibition of NCX1 attenuate hypoxia-induced pulmonary arterial hypertension.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.06.045
Abstract: The Na+/Ca2+ exchanger type-1 (NCX1) is a bidirectional transporter that is controlled by membrane potential and transmembrane gradients of Na+ and Ca2+. Vascular smooth muscle NCX1 plays an important role in intracellular Ca2+ homeostasis and… read more here.
Keywords: arterial hypertension; induced pulmonary; pulmonary arterial; ncx1 ... See more keywords
Myricetin ameliorates bleomycin-induced pulmonary fibrosis in mice by inhibiting TGF-β signaling via targeting HSP90β.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2020.114097
Abstract: Idiopathic pulmonary fibrosis is a progressive-fibrosing lung disease with high mortality and limited therapy, which characterized by myofibroblasts proliferation and extracellular matrix deposition. Myricetin, a natural flavonoid, has been shown to possess a variety of… read more here.
Keywords: hsp90; induced pulmonary; pulmonary fibrosis; tgf signaling ... See more keywords
Inula japonica ameliorated bleomycin-induced pulmonary fibrosis via inhibiting soluble epoxide hydrolase.
Sign Up to like & getrecommendations! Published in 2020 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2020.104065
Abstract: Pulmonary fibrosis is a progressive, irreversible, and fatal fibrotic lung disease with a high mortality and morbidity, and commonly nonresponsive to conventional therapy. Inula japonica Thunb. is a traditional Chinese medicine, known as "Xuan Fu… read more here.
Keywords: fibrosis; blm induced; induced pulmonary; inula japonica ... See more keywords