Articles with "induced pxr" as a keyword



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Identification of novel pregnane X receptor (PXR) agonists by In silico and biological activity analyses and reversal of cigarette smoke-induced PXR downregulation.

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Published in 2021 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2021.02.145

Abstract: Cigarette smoke (CS) contains many toxins that collectively harm nearly every organ in the body, and smoking is a key risk factor for many chronic diseases. Aside from its toxic actions, CS may alter expression… read more here.

Keywords: receptor pxr; cigarette smoke; pxr; pregnane receptor ... See more keywords