Chitinase1 contributed to a potential protection via microglia polarization and Aβ oligomer reduction in D-galactose and aluminum-induced rat model with cognitive impairments
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2017.04.050
Abstract: Chitinase activity is increased in Alzheimer's disease (AD). However, the role of chitinase1 in AD is unknown. We investigated the effects of chitinase1 on Alzheimer's pathology and microglia function. Artificial chitinase1 and chitinase inhibitor (chitinase-IN-2)… read more here.
Keywords: model cognitive; cognitive impairments; induced rat; galactose alcl3 ... See more keywords
The Ameliorative Impact of Centella Asiatica on Working Memory Deficit in STZ-Induced Rat Model of Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2021 at "Basic and clinical neuroscience"
DOI: 10.32598/bcn.2021.144.4
Abstract: Alzheimer's disease (AD) is a complex neurodegenerative disorder with a progressive template leading to neural damage as well as cognitive and memory deficit. The present study designed to investigate the neuroprotective effects of Centella Asiatica… read more here.
Keywords: stz induced; memory; stz; induced rat ... See more keywords
Combined Ubisol-Q10 and Ashwagandha Root Extract Target Multiple Biochemical Mechanisms and Reduces Neurodegeneration in a Paraquat-Induced Rat Model of Parkinson’s Disease
Sign Up to like & getrecommendations! Published in 2021 at "Antioxidants"
DOI: 10.3390/antiox10040563
Abstract: Parkinson’s disease (PD) is characterized by progressive neurodegeneration in the substantia nigra (SN) region resulting in loss of movement coordination. Current therapies only provide symptomatic relief, and there is no agent to halt the progression… read more here.
Keywords: induced rat; treatment; ubisol q10; parkinson disease ... See more keywords
Preventive Potential of Resveratrol in Carcinogen-Induced Rat Thyroid Tumorigenesis
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DOI: 10.3390/nu10030279
Abstract: Thyroid cancer (TC) is the most common endocrine malignancy without reliable preventive agent. Resveratrol possesses in vitro anti-TC activities; while its effect(s) on thyroid tumorigenesis remains unknown. This study aims to address this issue using… read more here.
Keywords: resveratrol; thyroid tumorigenesis; induced rat; group ... See more keywords
Effects of (-)-epigallocatechin-3-gallate on cyclooxygenase 2 and matrix metalloproteinase 3, 9,13 expression induced by IL-1ß in rat meniscal fibrochondrocytes
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Food and Drug Analysis"
DOI: 10.38212/2224-6614.2583
Abstract: The objective of this study was to examine the effect of (-)-epigallocatechin-3-gallate (EGCG) on cyclooxygenase 2 (COX-2) and matrix metalloproteinase (MMP) 3, 9, and 13 expressions induced by IL-1b in rat meniscal fibrochondrocytes. Rat normal… read more here.
Keywords: cyclooxygenase; matrix metalloproteinase; induced rat; rat meniscal ... See more keywords