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   Articles with "induced raw264" as a keyword



Pyridazine and pyridazinone derivatives: Synthesis and in vitro investigation of their anti‐inflammatory potential in LPS‐induced RAW264.7 macrophages

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recommendations! Published in 2024 at "Drug Development Research"

DOI: 10.1002/ddr.22173

Abstract: New pyridazine and pyridazinone derivatives 3a–g, 4a–f, 6a, and 6b were designed and synthesized. Cell viability of all compounds was established based on the viability of lipopolysaccharide‐induced RAW264.7 macrophage cells determined via the MTT assay.… read more here.

Keywords: anti inflammatory; pyridazinone derivatives; derivatives synthesis; pyridazine pyridazinone ... See more keywords

Cynaropicrin attenuates inflammatory cytokines in LPS‐induced RAW264.7 cells and ovalbumin‐induced asthmatic mice

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recommendations! Published in 2024 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.23836

Abstract: This study examines the anti‐inflammatory activity of cynaropicrin against lipopolysaccharide (LPS) in vitro and ovalbumin (OVA)‐challenged asthma in mice. Cynaropicrin's antimicrobial effects were tested on Escherichia coli (E. coli) and Streptococcus pyogenes (S. pyogenes) using… read more here.

Keywords: mice; raw264 cells; asthmatic mice; cynaropicrin ... See more keywords
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Design, synthesis, in vitro determination and molecular docking studies of 4-(1-(tert-butyl)-3-phenyl-1H-pyrazol-4-yl) pyridine derivatives with terminal sulfonamide derivatives in LPS-induced RAW264.7 macrophage cells

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recommendations! Published in 2021 at "Medicinal Chemistry Research"

DOI: 10.1007/s00044-021-02784-9

Abstract: In the present work, a new series of 4-(1-(tert-butyl)-3-phenyl-1H-pyrazol-4-yl) pyridine possessing terminal ethyl or propyl sulfonamides was designed and synthesized. The cytotoxic effect of the final compounds was measured by applying MTT assay in LPS-Induced… read more here.

Keywords: raw264 macrophage; lps induced; butyl phenyl; tert butyl ... See more keywords
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Clematichinenoside AR Alleviates Foam Cell Formation and the Inflammatory Response in Ox-LDL-Induced RAW264.7 Cells by Activating Autophagy

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recommendations! Published in 2020 at "Inflammation"

DOI: 10.1007/s10753-020-01375-x

Abstract: Foam cell formation and inflammation in macrophages contribute to the development of atherosclerosis (AS). Clematichinenoside AR (AR) is a major active ingredient extracted from the traditional Chinese herb Clematis chinensis and has potent pharmacological effects… read more here.

Keywords: cell formation; foam cell; formation; induced raw264 ... See more keywords

Isotrifoliol inhibits pro‐inflammatory mediators by suppression of TLR/NF‐&kgr;B and TLR/MAPK signaling in LPS‐induced RAW264.7 cells☆

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recommendations! Published in 2017 at "International Immunopharmacology"

DOI: 10.1016/j.intimp.2017.01.033

Abstract: &NA; Soybeans, produced by Glycine max (L.) Merr., contain high levels of isoflavones, such as genistein and daidzein. However, soy leaves contain more diverse and abundant flavonol glycosides and coumestans, as compared to the soybean.… read more here.

Keywords: anti inflammatory; lps induced; isotrifoliol; tlr ... See more keywords

Establishment of a High Content Image Platform to Measure NF-κB Nuclear Translocation in LPS-Induced RAW264.7 Macrophages for Screening Anti-inflammatory Drug Candidates.

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recommendations! Published in 2022 at "Current drug metabolism"

DOI: 10.2174/1389200223666220411121614

Abstract: BACKGROUND High content image (HCI), an automatic imaging and analysis system, provides a fast drug screening method by detecting the subcellular distribution of protein in intact cells. OBJECTIVE This study established the first standardized HCI… read more here.

Keywords: platform; translocation; induced raw264; anti inflammatory ... See more keywords

Urolithin A Inactivation of TLR3/TRIF Signaling to Block the NF-κB/STAT1 Axis Reduces Inflammation and Enhances Antioxidant Defense in Poly(I:C)-Induced RAW264.7 Cells

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recommendations! Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23094697

Abstract: Urolithin A is an active compound of gut-microbiota-derived metabolites of polyphenol ellagic acid that has anti-aging, antioxidative, and anti-inflammatory effects. However, the effects of urolithin A on polyinosinic acid-polycytidylic acid (poly(I:C))-induced inflammation remain unclear. Poly(I:C)… read more here.

Keywords: inflammation; poly induced; induced raw264; raw264 cells ... See more keywords

Proteoglycan from Bacillus sp. BS11 Inhibits the Inflammatory Response by Suppressing the MAPK and NF-κB Pathways in Lipopolysaccharide-Induced RAW264.7 Macrophages

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recommendations! Published in 2020 at "Marine Drugs"

DOI: 10.3390/md18120585

Abstract: Inflammation is involved in the pathogenesis of many debilitating diseases. Proteoglycan isolated from marine Bacillus sp. BS11 (EPS11) was shown to have anticancer activity, but its anti-inflammatory potential remains elusive. In the present study, the… read more here.

Keywords: anti inflammatory; raw264 macrophages; induced raw264; bacillus bs11 ... See more keywords