A genome-wide screen identifies SCAI as a modulator of the UV-induced replicative stress response
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DOI: 10.1371/journal.pbio.3001543
Abstract: Helix-destabilizing DNA lesions induced by environmental mutagens such as UV light cause genomic instability by strongly blocking the progression of DNA replication forks (RFs). At blocked RF, single-stranded DNA (ssDNA) accumulates and is rapidly bound… read more here.
Keywords: dna; stress response; induced replicative; replicative stress ... See more keywords