Effect of human umbilical cord blood mesenchymal stem cells administered by intravenous or intravitreal routes on cryo‐induced retinal injury
Sign Up to like & getrecommendations! Published in 2017 at "IUBMB Life"
DOI: 10.1002/iub.1608
Abstract: Traumatic optic neuropathy is an important cause of severe vision loss. So, many attempts were performed to transplant stem cells systemically or locally to regenerate the injured retina. In this study, we investigated the effect… read more here.
Keywords: stem cells; induced retinal; cryo induced; mice ... See more keywords
Segmentation of laser induced retinal lesions using deep learning (December 2021)
Sign Up to like & getrecommendations! Published in 2022 at "Lasers in Surgery and Medicine"
DOI: 10.1002/lsm.23578
Abstract: Detection of retinal laser lesions is necessary in both the evaluation of the extent of damage from high power laser sources, and in validating treatments involving the placement of laser lesions. However, such lesions are… read more here.
Keywords: laser; induced retinal; deep learning; segmentation laser ... See more keywords
Isoliquiritigenin downregulates miR-195 and attenuates oxidative stress and inflammation in STZ-induced retinal injury
Sign Up to like & getrecommendations! Published in 2020 at "Naunyn-Schmiedeberg's Archives of Pharmacology"
DOI: 10.1007/s00210-020-01948-5
Abstract: Diabetic retinopathy (DR) is a major microvascular complication of diabetes mellitus that leads to significant vision loss. Isoliquiritigenin (ISL) is a bioactive flavonoid found in the root of licorice with reported anti-oxidant and anti-inflammatory activities.… read more here.
Keywords: retinal injury; mir 195; induced retinal; oxidative stress ... See more keywords
Optical coherence tomography angiography for screening of hydroxychloroquine-induced retinal alterations
Sign Up to like & getrecommendations! Published in 2018 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-018-4117-3
Abstract: Background/aimsThe purpose of the study was to evaluate the retinal and choroidal changes via optical coherence tomography angiography (OCTA) in patients who received hydroxychloroquine (HCQ).MethodsSixty eyes of 60 female patients who received HCQ were included… read more here.
Keywords: risk group; risk; induced retinal; hcq ... See more keywords
Ferrostatin-1 attenuates ferroptosis and protects the retina against light-induced retinal degeneration.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.02.055
Abstract: Degenerative retinal diseases, including age-related macular degeneration, are serious diseases that may lead to irreversible retinal neuron damage and permanent vision impairment. There are currently no effective treatments for these diseases due to our incomplete… read more here.
Keywords: induced retinal; light induced; ferroptosis; retinal degeneration ... See more keywords
Exosomes derived from platelet-rich plasma mediate hyperglycemia-induced retinal endothelial injury via targeting the TLR4 signaling pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Experimental eye research"
DOI: 10.1016/j.exer.2019.107813
Abstract: In this study, we aimed to investigate whether exosomes derived from platelet-rich plasma (PRP-Exos) can regulate hyperglycemia-induced retinal injury via targeting the TLR4 signaling pathway. We studied the effects of PRP-Exos on retinal endothelial injury… read more here.
Keywords: endothelial injury; induced retinal; prp exos; injury ... See more keywords
Lutein protected the retina from light induced retinal damage by inhibiting increasing oxidative stress and inflammation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2020.104107
Abstract: Abstract The present study aimed to evaluate the effects of lutein on blue LED light-induced retinal injury. Animals were randomly assigned to six groups. Distilled water (normal control and water-light group), corn oil (solvent-light group),… read more here.
Keywords: induced retinal; light induced; light; lutein protected ... See more keywords
Identification of aberrantly expressed circular RNAs in hyperlipidemia-induced retinal vascular dysfunction in mice.
Sign Up to like & getrecommendations! Published in 2020 at "Genomics"
DOI: 10.1016/j.ygeno.2020.09.055
Abstract: Hyperlipidemia-induced retinal vascular dysfunction is a complex pathological process. circRNAs are important regulators of biological processes and disease progression. However, the expression pattern of circRNAs in hyperlipidemia-induced retinal vascular dysfunction remains unclear. Herein, we used… read more here.
Keywords: retinal vascular; ontology; induced retinal; hyperlipidemia ... See more keywords
Flicker‐induced retinal vascular dilation in ipsi‐ and contralateral eyes of patients with carotid stenosis before and after carotid endarterectomy: a prospective study
Sign Up to like & getrecommendations! Published in 2022 at "Acta Ophthalmologica"
DOI: 10.1111/aos.15107
Abstract: Retinal vascular function was assessed in patients with carotid stenosis (CS) before and six months after carotid endarterectomy (CEA) and in controls at a six‐month interval. read more here.
Keywords: carotid stenosis; induced retinal; patients carotid; flicker induced ... See more keywords
Protection against light-induced retinal degeneration via dual anti-inflammatory and anti-angiogenic functions of thrombospondin-1.
Sign Up to like & getrecommendations! Published in 2020 at "British journal of pharmacology"
DOI: 10.1111/bph.15303
Abstract: BACKGROUND AND PURPOSE Retinal photodamage is a high-risk factor for age-related macular degeneration (AMD), the leading cause of irreversible blindness worldwide. However, both the pathogenesis and effective therapies for retinal photodamage remain unclear and controversial.… read more here.
Keywords: blue light; anti inflammatory; induced retinal; light induced ... See more keywords
tRNA‐derived fragment tRF‐1020 ameliorates diabetes‐induced retinal microvascular complications
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17555
Abstract: Transfer RNA (tRNA)‐derived fragments are the non‐coding single‐stranded RNAs involved in several physiological and pathological processes. Herein, we investigated the role of tRF‐1020, a tRNA fragment, in diabetes‐induced retinal microvascular complications. The results showed that… read more here.
Keywords: trf; retinal microvascular; induced retinal; trf 1020 ... See more keywords