Ubiquitin-induced RNF168 condensation promotes DNA double-strand break repair
Sign Up to like & getrecommendations! Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2322972121
Abstract: Significance We demonstrated that RNF168 underwent liquid–liquid phase separation at the double-strand break (DSB) sites driven by both the intrinsically disordered region and the interaction with K63-linked polyubiquitin chains. Irradiation-induced RNF168 condensation accelerated the accumulation… read more here.
Keywords: induced rnf168; strand break; rnf168 condensation; double strand ... See more keywords