Pilot study of inflammatory biomarkers in matched induced sputum and bronchoalveolar lavage of 2‐year‐olds with cystic fibrosis
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.26023
Abstract: In this pilot study, we investigated whether induced sputum (IS) could serve as a viable alternative to bronchoalveolar lavage (BAL) and yield robust inflammatory biomarkers in toddlers with cystic fibrosis (CF) featuring minimal structural lung… read more here.
Keywords: induced sputum; inflammatory biomarkers; bronchoalveolar lavage; pilot study ... See more keywords
Application of Inflammatory Markers in Induced Sputum in Stable Chronic Obstructive Pulmonary Disease Patients with Positive Bronchodilation Tests
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DOI: 10.1007/s11596-019-2074-7
Abstract: SummaryPositive bronchodilation (BD) tests can be noticed in some stable chronic obstructive pulmonary disease (COPD) patients. The characteristics of airway inflammation in this entity remain unclear. Our study aimed to identify the characteristics of airway… read more here.
Keywords: positive tests; patients positive; copd patients; induced sputum ... See more keywords
The effect of BCG vaccination on alveolar macrophages obtained from induced sputum from healthy volunteers.
Sign Up to like & getrecommendations! Published in 2020 at "Cytokine"
DOI: 10.1016/j.cyto.2020.155135
Abstract: The anti-tuberculosis vaccine Bacillus Calmette-Guérin (BCG) is able to boost innate immune responses through a process called 'trained immunity'. It is hypothesized that BCG-induced trained immunity contributes to protection against Mycobacterium tuberculosis infection. Since alveolar… read more here.
Keywords: vaccination alveolar; alveolar macrophages; bcg vaccination; induced sputum ... See more keywords
Elevated eosinophils, IL5 and IL8 in induced sputum in asthma patients with accelerated FEV1 decline.
Sign Up to like & getrecommendations! Published in 2020 at "Respiratory medicine"
DOI: 10.1016/j.rmed.2020.105875
Abstract: BACKGROUND Some patients with asthma present with accelerated lung function decline. This phenomenon is mostly associated with severe exacerbations and with poor asthma control. OBJECTIVE Our aim was to detect the extent of FEV1 decline… read more here.
Keywords: fev1 decline; decline; induced sputum; eosinophils il5 ... See more keywords
Inflammatory profile of induced sputum composition in systemic sclerosis and comparison with healthy volunteers
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DOI: 10.1038/s41598-021-87701-1
Abstract: Systemic sclerosis (SSc) is a potentially serious and disabling connective tissue disease specially in case of interstitial lung disease (SSc-ILD). The aim of our study was to evaluate the potential utility of dosing in the… read more here.
Keywords: ssc patients; ssc; ssc ild; systemic sclerosis ... See more keywords
PO 8596 ENHANCING LABORATORY DIAGNOSIS OF MYCOBACTERIUM TUBERCULOSIS IN SAMPLES FROM CHILDREN IN THE GAMBIA
Sign Up to like & getrecommendations! Published in 2019 at "BMJ Global Health"
DOI: 10.1136/bmjgh-2019-edc.160
Abstract: Background Routine laboratory diagnostic methods for M. Tuberculosis complex (MTBC) in induced sputum samples such as smear microscopy, GeneXpert and liquid Mycobacteria growth indicator tube (MGIT) culture are often negative due to the paucibacillary nature… read more here.
Keywords: diagnosis; mtbc; microscopy; prolonged incubation ... See more keywords
Elevated CEACAM5 Levels in Patients with Asthma
Sign Up to like & getrecommendations! Published in 2022 at "International Archives of Allergy and Immunology"
DOI: 10.1159/000521754
Abstract: Introduction: Asthma is a common chronic respiratory disease. This study aimed to explore the expression level of carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) in induced sputum supernatant, induced sputum cells, and serum of asthma… read more here.
Keywords: induced sputum; sputum supernatant; ceacam5 induced; expression ... See more keywords
Correlation between Increased Monocyte Chemotactic Protein 1 Level and Lung Function in Patients with Asthma
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DOI: 10.1159/000521946
Abstract: Background: The altered expression of monocyte chemotactic protein 1 (MCP1) in bronchoalveolar fluid was observed in patients and animal models of allergic asthma. However, the correlation between induced sputum MCP1 level and asthma clinical features… read more here.
Keywords: lung function; patients asthma; induced sputum; mcp1 level ... See more keywords
Increased SERPINB10 Expression in Induced Sputum Was Associated with Airway Type 2 Inflammation in Asthma
Sign Up to like & getrecommendations! Published in 2022 at "International Archives of Allergy and Immunology"
DOI: 10.1159/000524613
Abstract: Background: Asthma is a common chronic airway inflammation in the world. The aim of this study was to investigate the expression of SERPINB10 in induced sputum and its correlation with airway type 2 inflammation in… read more here.
Keywords: induced sputum; airway type; type inflammation; inflammation ... See more keywords
Elevated CXCL14 in Induced Sputum Was Associated with Eosinophilic Inflammation and Airway Obstruction in Patients with Asthma
Sign Up to like & getrecommendations! Published in 2022 at "International Archives of Allergy and Immunology"
DOI: 10.1159/000526367
Abstract: Introduction: CXCL14 involved in inflammatory processes was upregulated in the asthma expression profile datasets in our pilot study. However, the expression of CXCL14 in induced sputum and its potential clinical role in asthma were poorly… read more here.
Keywords: induced sputum; inflammation; cxcl14 induced; expression ... See more keywords
Diagnosing Pulmonary Tuberculosis by Pooling Induced Sputum
Sign Up to like & getrecommendations! Published in 2017 at "European Respiratory Journal"
DOI: 10.1183/1393003.congress-2017.pa2740
Abstract: Introduction: Early diagnosis and treatment of pulmonary tuberculosis (PTB) remains fundamental in reducing transmissions and death. Sputum induction is recommended for the diagnosis of pulmonary tuberculosis (PTB) in patients who are unable to expectorate or… read more here.
Keywords: 100 100; pulmonary tuberculosis; ptb; sputum ... See more keywords