BRAF‐V600E utilizes posttranscriptional mechanisms to amplify LPS‐induced TNFα production in dendritic cells in a mouse model of Langerhans cell histiocytosis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3a0122-075rr
Abstract: Langerhans cell histiocytosis (LCH) is an inflammatory disease characterized by abnormal dendritic cells (DCs) with hyperactive ERK signaling, called “LCH cells.” Since DCs rely on ERK signaling to produce inflammatory molecules in response to pathogenic… read more here.
Keywords: tnf production; tnf; biology; induced tnf ... See more keywords
IL-3 inhibits rat osteoclast differentiation induced by TNF-α and other pro-osteoclastogenic cytokines.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of biosciences"
DOI: 10.1007/s12038-021-00181-3
Abstract: IL-3, a haematopoiesis regulatory factor, has previously been shown to inhibit both mouse and human osteoclast differentiation and bone resorption. Here, the role of rat IL-3 on rat osteoclast differentiation was evaluated to address whether… read more here.
Keywords: osteoclast differentiation; differentiation induced; induced tnf; differentiation ... See more keywords
Lipopolysaccharide-induced TNFα factor (LITAF) promotes inflammatory responses and activates apoptosis in zebrafish Danio rerio.
Sign Up to like & getrecommendations! Published in 2021 at "Gene"
DOI: 10.1016/j.gene.2021.145487
Abstract: Lipopolysaccharide-induced TNFα factor (LITAF) is an important transcription factor which activates the transcription of TNFα and regulates cell apoptosis and inflammatory response. In the present study, a LITAF gene homologue was identified in zebrafish (Danio… read more here.
Keywords: factor litaf; lipopolysaccharide induced; tnf factor; induced tnf ... See more keywords
Ebosin Attenuates the Inflammatory Responses Induced by TNF-α through Inhibiting NF-κB and MAPK Pathways in Rat Fibroblast-Like Synoviocytes
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/9166370
Abstract: Tumor necrosis factor-α (TNF-α) lies at the apex of signal transduction cascades that results in induced destruction of joints in rheumatoid arthritis. It is therefore of great medicinal interest to modulate the cellular responses to… read more here.
Keywords: rat fibroblast; mapk pathways; like synoviocytes; fibroblast like ... See more keywords
A novel AMPK activator hernandezine inhibits LPS-induced TNFα production.
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.18365
Abstract: Here, we found that hernandezine, a novel AMPK activator, inhibited LPS-induced TNFα expression/production in human macrophage cells (THP-1 and U937 lines). Activation of AMPK is required for hernandezine-induced anti-LPS response. AMPKα shRNA or dominant negative… read more here.
Keywords: lps induced; production; induced tnf; ampk ... See more keywords