Direct Reprogramming of Mouse Embryonic Fibroblasts to Induced Trophoblast Stem Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0301-7_18
Abstract: Trophoblast cells are the first committed lineage to emerge during mammalian preimplantation embryo development. Trophoblast stem (TS) cells can be derived from the trophectoderm (TE) of blastocyst-stage embryos and differentiate into extraembryonic trophoblast cells of the… read more here.
Keywords: induced trophoblast; trophoblast; stem cells; trophoblast stem ... See more keywords
Forkhead-box C1 attenuates high glucose-induced trophoblast cell injury during gestational diabetes mellitus via activating adenosine monophosphate-activated protein kinase through regulating fibroblast growth factor 19
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2018094
Abstract: ABSTRACT Gestational diabetes mellitus (GDM) is a complication developed during pregnancy and recover after childbirth. The purpose of this study was to investigate the protective role of FOXC1 during GDM and the underlying mechanism. FOXC1… read more here.
Keywords: cell; trophoblast cell; gestational diabetes; diabetes mellitus ... See more keywords
Antiphospholipid antibody‐induced trophoblast responses are differentially modulated by viral dsRNA and viral ssRNA
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DOI: 10.1111/aji.13516
Abstract: Women with antiphospholipid antibodies (aPL) are at increased risk for pregnancy loss and preeclampsia. aPL target the trophoblast and induce a pro‐inflammatory, anti‐angiogenic and anti‐migratory profile. Since infection during pregnancy can increase the risk for… read more here.
Keywords: differentially modulated; induced trophoblast; antiphospholipid antibody; responses differentially ... See more keywords