Pharmacological inhibition of IRAK1 attenuates colitis‐induced tumorigenesis in mice by inhibiting the inflammatory response and epithelial–mesenchymal transition
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22838
Abstract: Colorectal cancer (CRC) is the third most common type of cancer. Here, we studied the inhibitory effect of IRAK1 and IRAK4 as a preventive strategy using a colitis‐induced tumorigenesis mouse model. CRC clinical data were… read more here.
Keywords: induced tumorigenesis; irak1 inhibitor; colitis induced; epithelial mesenchymal ... See more keywords
Epigenetic Regulation in Exposome-Induced Tumorigenesis: Emerging Roles of ncRNAs
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DOI: 10.3390/biom12040513
Abstract: Environmental factors, including pollutants and lifestyle, constitute a significant role in severe, chronic pathologies with an essential societal, economic burden. The measurement of all environmental exposures and assessing their correlation with effects on individual health… read more here.
Keywords: induced tumorigenesis; regulation; exposome induced; noncoding rnas ... See more keywords