Evaluating VEGF-Induced Vascular Leakage Using the Miles Assay.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-2217-9_21
Abstract: Before the endothelial mitogenic activity of the Vascular Endothelial Growth Factor A (VEGF) was described, VEGF had already been identified for its ability to induce vascular leakage. VEGF-induced vascular leakage has been most frequently studied… read more here.
Keywords: using miles; induced vascular; vegf induced; vascular leakage ... See more keywords
Overexpression of Sirtuin2 prevents high glucose-induced vascular endothelial cell injury by regulating the p53 and NF-κB signaling pathways
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology Letters"
DOI: 10.1007/s10529-017-2487-y
Abstract: ObjectivesTo investigate the potential role and underlying mechanism of Sirtuin2 (SIRT2) in regulating high glucose (HG)-induced vascular endothelial cell injury by using human umbilical vein endothelial cells (HUVECs).ResultsSIRT2 mRNA and protein expression levels were decreased… read more here.
Keywords: cell injury; endothelial cell; induced vascular; vascular endothelial ... See more keywords
Radiation-induced vascular malformations in the brain, mimicking tumor in MRI-based treatment response assessment maps (TRAMs)
Sign Up to like & getrecommendations! Published in 2019 at "Clinical and Translational Radiation Oncology"
DOI: 10.1016/j.ctro.2018.11.004
Abstract: Highlights • Of 310 brain tumors patients recruited, histology of 99 lesions was available.• Of those, 5 were histologically confirmed as radiation-induced malformations.• TRAMs cannot differentiate active tumor from vascular malformation. read more here.
Keywords: radiation induced; vascular malformations; radiation; induced vascular ... See more keywords
Inhibition of semaphorin-3a alleviates lipopolysaccharide-induced vascular injury.
Sign Up to like & getrecommendations! Published in 2022 at "Microvascular research"
DOI: 10.1016/j.mvr.2022.104346
Abstract: Alleviating vascular injury improves the prognosis of atherosclerosis. Semaphorin-3a (Sema3A) is a special membrane-associated secreted protein with various biological properties, like pro-inflammation, anti-tumor and et al. This study aims to investigate the effects of inhibition… read more here.
Keywords: inhibition sema3a; induced vascular; injury; inhibition ... See more keywords
The Protective Effects of Tripeptides VPP and IPP against Small Extracellular Vesicles from Angiotensin II-Induced Vascular Smooth Muscle Cells Mediating Endothelial Dysfunction in Human Umbilical Vein Endothelial Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.0c05698
Abstract: Endothelial dysfunction is a common disorder of vascular homeostasis in hypertension characterized by oxidative stress, malignant migration, inflammatory response, and active adhesion response of endothelial cells. The extracellular vesicles (EVs), a vital participant in vascular… read more here.
Keywords: extracellular vesicles; vpp ipp; dysfunction; endothelial cells ... See more keywords
Cold-induced Vascular Changes in the Macula, Optic Disc and Choroid in Children with Raynaud’s Phenomena
Sign Up to like & getrecommendations! Published in 2022 at "Ocular Immunology and Inflammation"
DOI: 10.1080/09273948.2022.2026411
Abstract: ABSTRACT Aim To investigate changes in retinal and choroidal vessels in children with primary and secondary raynaud’s phenomena(RP). Methods Measurements were performed by optic coherence tomography angiography before as well as during and 10 minutes… read more here.
Keywords: raynaud phenomena; macula optic; induced vascular; vascular changes ... See more keywords
The therapeutic relevance of the Kallikrein-Kinin axis in SARS-cov-2-induced vascular pathology
Sign Up to like & getrecommendations! Published in 2022 at "Critical Reviews in Clinical Laboratory Sciences"
DOI: 10.1080/10408363.2022.2102578
Abstract: Abstract While coronavirus disease 2019 (COVID-19) begins as a respiratory infection, it progresses as a systemic disease involving multiorgan microthromboses that underly the pathology. SARS-CoV-2 enters host cells via attachment to the angiotensin-converting enzyme 2… read more here.
Keywords: kallikrein kinin; cov induced; pathology; sars cov ... See more keywords
Angiotensin-(1-7) ameliorates high glucose-induced vascular endothelial injury through suppressing chloride channel 3
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.1997695
Abstract: ABSTRACT Diabetes Mellitus (DM) is a significant risk factor for cardiovascular disease (CVD), which is leading cause of deaths in DM patients. However, there are limited effective medical therapies for diabetic CVD. Vascular endothelial injury… read more here.
Keywords: endothelial injury; diabetic cvd; injury; vascular endothelial ... See more keywords
Resveratrol Mitigates High-Fat Diet–Induced Vascular Dysfunction by Activating the Akt/eNOS/NO and Sirt1/ER Pathway
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000000621
Abstract: Abstract: We investigated whether resveratrol (RSV) can attenuate obesity and diabetes progression and improve diabetes-induced vascular dysfunction, and we attempted to delineate its underlying mechanisms. Male C57Bl/6 mice were administered a high-fat diet (HFD) for… read more here.
Keywords: rsv; sirt1 pathway; vascular dysfunction; induced vascular ... See more keywords
Nebivolol Improves Obesity-Induced Vascular Remodeling by Suppressing NLRP3 Activation.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000000667
Abstract: Nebivolol is a novel β-adrenergic receptor (β-AR) blocker with anti-inflammatory and antioxidant properties. The NLRP3 inflammasome plays a pivotal role in the pathogenesis of obesity-induced vascular dysfunction. Our study aimed to explore the effect of… read more here.
Keywords: induced vascular; activation; obesity induced; nlrp3 inflammasome ... See more keywords
HDAC Inhibitors Alleviate Uric Acid–Induced Vascular Endothelial Cell Injury by Way of the HDAC6/FGF21/PI3K/AKT Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000001372
Abstract: Supplemental Digital Content is Available in the Text. Abstract: Uric acid (UA) accumulation triggers endothelial dysfunction, oxidative stress, and inflammation. Histone deacetylase (HDAC) plays a vital role in regulating the pathological processes of various diseases.… read more here.
Keywords: cell; endothelial cell; uric acid; injury ... See more keywords