Optimization of the T3-induced Xenopus metamorphosis assay for detecting thyroid hormone signaling disruption of chemicals.
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DOI: 10.1016/j.jes.2016.09.020
Abstract: T3-induced Xenopus metamorphosis is an ideal model for detecting thyroid hormone (TH) signaling disruption of chemicals. To optimize the T3-induced Xenopus assay and improve its sensitivity and reproducibility, we intend to develop quantitatively morphological endpoints… read more here.
Keywords: signaling disruption; detecting thyroid; xenopus metamorphosis; induced xenopus ... See more keywords
Re-evaluation of thyroid hormone signaling antagonism of tetrabromobisphenol A for validating the T3-induced Xenopus metamorphosis assay.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of environmental sciences"
DOI: 10.1016/j.jes.2016.09.021
Abstract: We developed the T3-induced Xenopus metamorphosis assay, which is supposed to be able to sensitively detect thyroid hormone (TH) signaling disruption of chemicals. The present study aimed to validate the T3-induced Xenopus metamorphosis assay by… read more here.
Keywords: hormone signaling; metamorphosis assay; xenopus metamorphosis; induced xenopus ... See more keywords