Hedgehog-induced ZFYVE21 promotes chronic vascular inflammation by activating NLRP3 inflammasomes in T cells
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DOI: 10.1126/scisignal.abo3406
Abstract: The zinc finger protein ZFYVE21 is involved in immune signaling. Using humanized mouse models, primary human cells, and patient samples, we identified a T cell–autonomous role for ZFYVE21 in promoting chronic vascular inflammation associated with… read more here.
Keywords: inflammation; vascular inflammation; chronic vascular; nlrp3 inflammasomes ... See more keywords