Scutellarin derivatives as apoptosis inducers: Design, synthesis and biological evaluation.
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DOI: 10.1016/j.ejmech.2017.03.020
Abstract: To explore novel antitumor agents with high efficiency and low toxicity, a series of NO-donating scutellarin derivatives (14-17) were synthesized and the antiproliferative activities against MCF-7, HCT-116, PC-3 and HepG2 cancer cell lines were assessed.… read more here.
Keywords: design synthesis; scutellarin derivatives; derivatives apoptosis; inducers design ... See more keywords