Blue light induces apoptosis and autophagy by promoting ROS‐mediated mitochondrial dysfunction in synovial sarcoma
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Medicine"
DOI: 10.1002/cam4.5664
Abstract: Synovial sarcoma (SS) has limited treatment options and there is an urgent need to develop a novel therapeutic strategy to treat SS. Blue light (BL) has been shown to inhibit the growth of several cancer… read more here.
Keywords: light induces; apoptosis autophagy; blue light; induces apoptosis ... See more keywords
β‐Elemene induces apoptosis by activating the P53 pathway in human hypertrophic scar fibroblasts
Sign Up to like & getrecommendations! Published in 2022 at "IUBMB Life"
DOI: 10.1002/iub.2614
Abstract: Hypertrophic scar (HS) is a condition characterized by excessive synthesis and deposition of collagen. There are many clinical methods to alleviate HS, but most of them are accompanied by many complications. To investigate the effects… read more here.
Keywords: hypertrophic scar; scar; p53; induces apoptosis ... See more keywords
Corilagin induces apoptosis and inhibits HMBG1/PI3K/AKT signaling pathways in a rat model of gastric carcinogenesis induced by methylnitronitrosoguanidine
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23478
Abstract: Gastric cancer, invasive cancer of the gastrointestinal tract, found in developing countries. Chemotherapy to patients with advanced gastric cancer, exhibits greater drug resistance to standard chemotherapy drugs. Therefore, important to establish anti‐cancer drugs that are… read more here.
Keywords: corilagin; apoptosis inhibits; gastric cancer; induces apoptosis ... See more keywords
Thymoquinone induces apoptosis in temozolomide‐resistant glioblastoma cells via the p38 mitogen‐activated protein kinase signaling pathway
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23664
Abstract: Temozolomide (TMZ) can cross the blood‐brain barrier (BBB) and deliver methyl groups to the purine (guanine) bases of DNA, leading to mispairing during DNA replication and subsequent cell death. However, increased expression of the repair… read more here.
Keywords: mitogen activated; protein kinase; activated protein; p38 mitogen ... See more keywords
Selenium Deficiency Induces Apoptosis, Mitochondrial Dynamic Imbalance, and Inflammatory Responses in Calf Liver.
Sign Up to like & getrecommendations! Published in 2022 at "Biological trace element research"
DOI: 10.1007/s12011-021-03059-5
Abstract: Selenium (Se) deficiency significantly impacts the cow breeding industry by reducing the milk quality of dairy cows and affecting the health of calves. The molecular mechanism of Se deficiency-induced damage to calves, however, remains unclear.… read more here.
Keywords: calf liver; induces apoptosis; deficiency induces; deficiency ... See more keywords
Timosaponin AIII induces apoptosis and autophagy in human melanoma A375-S2 cells
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Pharmacal Research"
DOI: 10.1007/s12272-016-0763-3
Abstract: Timosaponin AIII (AIII), a steroidal saponin isolated from Anemarrhena asphodeloides Bge. Our study showed that AIII induced both apoptosis and autophagy, and autophagy inhibited apoptosis in A375S2 cells. Furtherly, this study was carried out to… read more here.
Keywords: apoptosis autophagy; timosaponin aiii; aiii induces; autophagy human ... See more keywords
Mex-3B induces apoptosis by inhibiting miR-92a access to the Bim-3′UTR
Sign Up to like & getrecommendations! Published in 2018 at "Oncogene"
DOI: 10.1038/s41388-018-0336-7
Abstract: Cells respond to a variety of cellular stresses, including DNA damage, by regulating genes whose expression modulates cell cycle arrest, DNA repair, senescence, and/or apoptosis. MicroRNAs (miRNAs) play essential roles in both normal development and… read more here.
Keywords: mex induces; apoptosis inhibiting; mir 92a; bim ... See more keywords
Prednisolone induces apoptosis in corneal epithelial cells through the intrinsic pathway
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-04509-8
Abstract: Glucocorticoid eye drops are one of the most widely used medications in ophthalmology. However, little is known about the effects of glucocorticoids on corneal epithelial cells that are directly exposed to topically-administered glucocorticoids. Here we… read more here.
Keywords: epithelial cells; corneal epithelial; apoptosis corneal; induces apoptosis ... See more keywords
Quercetin modulates signaling pathways and induces apoptosis in cervical cancer cells
Sign Up to like & getrecommendations! Published in 2019 at "Bioscience Reports"
DOI: 10.1042/bsr20190720
Abstract: Cancer cells have the unique ability to overcome natural defense mechanisms, undergo unchecked proliferation and evade apoptosis. While chemotherapeutic drugs address this, they are plagued by a long list of side effects and have a… read more here.
Keywords: quercetin modulates; cancer cells; cancer; induces apoptosis ... See more keywords
Stem Hexane Extract of Strobilanthes crispus Induces Apoptosis in Triple-Negative Breast Cancer Cell Line.
Sign Up to like & getrecommendations! Published in 2021 at "Nutrition and cancer"
DOI: 10.1080/01635581.2021.1880606
Abstract: Strobilanthes crispus is known to possess multiple health beneficial effects and reported to be traditionally used as medicine in several countries. This study was to investigate the anti-proliferative effects of S. crispus leaves and stem… read more here.
Keywords: strobilanthes crispus; stem hexane; stem; cell ... See more keywords
miR‐129‐2 upregulation induces apoptosis and promotes NSCLC chemosensitivity by targeting SOX4
Sign Up to like & getrecommendations! Published in 2022 at "Thoracic Cancer"
DOI: 10.1111/1759-7714.14336
Abstract: As one of the main causes of death worldwide, the treatment of non‐small‐cell lung cancer (NSCLC) is still unsatisfactory. This study aimed to explore the role of miR‐129‐2 in cell apoptosis and NSCLC chemosensitivity. read more here.
Keywords: mir 129; induces apoptosis; 129 upregulation; upregulation induces ... See more keywords