Diethylstilbestrol (DES) induces autophagy in thymocytes by regulating Beclin-1 expression through epigenetic modulation.
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology"
DOI: 10.1016/j.tox.2018.08.012
Abstract: Diethylstilbestrol (DES) is an endocrine disruptor that was used to prevent adverse effects of pregnancy in women in late 1940s until early 1970s. Its use was banned following significant toxicity and negative effects not only… read more here.
Keywords: des induces; autophagy thymocytes; expression; induces autophagy ... See more keywords
FK506, an Immunosuppressive Drug, Induces Autophagy by Binding to the V-ATPase Catalytic Subunit A in Neuronal Cells.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.6b00638
Abstract: The drug FK506 (tacrolimus, fujimycin) exerts its immunosuppressive effects by regulating the nuclear factor of the activated T-cell (NFAT) family of transcription factors. However, FK506 also exhibits neuroprotective effects, but its direct target proteins that… read more here.
Keywords: fk506; catalytic subunit; target; drug ... See more keywords
Cannabidiol induces autophagy via ERK1/2 activation in neural cells
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DOI: 10.1038/s41598-021-84879-2
Abstract: Autophagy is a lysosomal catabolic process essential to cell homeostasis and is related to the neuroprotection of the central nervous system. Cannabidiol (CBD) is a non-psychotropic phytocannabinoid present in Cannabis sativa. Many therapeutic actions have… read more here.
Keywords: autophagy via; erk1 activation; induces autophagy; cannabidiol induces ... See more keywords
IL4 (interleukin 4) induces autophagy in B cells leading to exacerbated asthma
Sign Up to like & getrecommendations! Published in 2018 at "Autophagy"
DOI: 10.1080/15548627.2017.1421884
Abstract: ABSTRACT Allergic asthma is a common airway inflammatory disease in which B cells play important roles through IgE production and antigen presentation. SNP (single nucleotide polymorphism) analysis showed that Atg (autophagy-related) allele mutations are involved… read more here.
Keywords: il4 interleukin; induces autophagy; autophagy; autophagy cells ... See more keywords
Ambroxol Induces Autophagy and Potentiates Rifampin Antimycobacterial Activity
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DOI: 10.1128/aac.01019-18
Abstract: Host-directed therapy in tuberculosis is a potential adjunct to antibiotic chemotherapy directed at Mycobacterium tuberculosis. Ambroxol, a lead compound, emerged from a screen for autophagy-inducing drugs. ABSTRACT Host-directed therapy in tuberculosis is a potential adjunct… read more here.
Keywords: ambroxol induces; potentiates rifampin; tuberculosis; induces autophagy ... See more keywords
Arctigenin Inhibits Glioblastoma Proliferation through the AKT/mTOR Pathway and Induces Autophagy
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DOI: 10.1155/2020/3542613
Abstract: Purpose Arctigenin (ARG) is a natural lignan compound extracted from Arctium lappa and has displayed anticancer function and therapeutic effect in a variety of cancers. Arctigenin is mainly from Arctium lappa extract. It has been… read more here.
Keywords: mtor pathway; apoptosis; proliferation; mtor ... See more keywords
LINC01278 Induces Autophagy to Inhibit Tumour Progression by Suppressing the mTOR Signalling Pathway
Sign Up to like & getrecommendations! Published in 2023 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2023/8994901
Abstract: Uveal melanoma (UM) is an aggressive intraocular malignant tumour that is closely related to autophagic dysfunction. We aimed to identify autophagy-related long noncoding RNAs (lncRNAs) to elucidate the molecular mechanism of UM. Here, we show… read more here.
Keywords: mtor signalling; induces autophagy; linc01278 induces; autophagy inhibit ... See more keywords
Zinc Deficiency Induces Autophagy in HT-22 Mouse Hippocampal Neuronal Cell Line
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158811
Abstract: Zinc is a trace metal vital for various functions in nerve cells, although the effect of zinc deficiency on neuronal autophagy remains unclear. This study aimed to elucidate whether zinc deficiency induced by treatment with… read more here.
Keywords: zinc deficiency; cell; zinc; induces autophagy ... See more keywords
Resveratrol Inhibits Proliferation and Induces Autophagy by Blocking SREBP1 Expression in Oral Cancer Cells
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27238250
Abstract: Resveratrol is a polyphenolic antioxidant found in grapes, red wine, and peanuts and has been reported to have anti-neoplastic effects on various cancer types. However, the exact mechanism of its anti-cancer effects in oral cancer… read more here.
Keywords: cancer; resveratrol; oral cancer; induces autophagy ... See more keywords
Retracted: Safranal induces autophagy by AMPK activation and protects neurons against amyloid beta in Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2021 at "Tropical Journal of Pharmaceutical Research"
DOI: 10.4314/tjpr.v18i5.34
Abstract: This article has been retracted by the authors. read more here.
Keywords: induces autophagy; safranal induces; activation protects; ampk activation ... See more keywords